Results 121 to 130 of about 241,980 (309)

NIPAL1 Drives a Metabolic‐Epigenetic Feedback Loop to Promote Lactate‐Mediated Immune Evasion in Esophageal Cancer

Advanced Science, EarlyView.
The study identifies a NIPAL1‐driven metabolic‐epigenetic circuit in esophageal squamous cell carcinoma that promotes glycolysis, lactate accumulation, and H3K18 histone lactylation, forming a self‐sustaining loop that suppresses CD8+ T cell immunity.
Ri‐Xin Chen, Xiao‐Dan Ma, Shui‐Dan Xu, Ao‐Tian Mo, Min‐Hua Deng, Jun‐Han Wu, Wei‐Tao Zhuang, Jin‐Ling Duan, Shu‐Huan Xie, Jin‐Long Lin, Peng Lin, Ji‐Ming Tang, Hai‐Yu Zhou, Xiao‐Song Ben, Gui‐Bin Qiao, Dan Xie   +15 more
wiley   +1 more source

Space Processing Workshop [PDF]

Gravitational effects on electrodeposition were studied on the KC-135 aircraft parabolic flight paths. An experiment to investigate the effect of the hyperthermal atomic oxygen atmosphere on sensitive surfaces was flown on Space Shuttle Flight STS-18.

core   +1 more source

Synchrotron XRF Imaging Reveals Manganese Accumulation in the Golgi and Post‐Synapses of Neurons and Enhanced Uptake in Astrocytes

Advanced Science, EarlyView.
Despite widespread exposure, the mechanisms of manganese neurotoxicity remain poorly understood. Using correlative cryogenic fluorescence and synchrotron X‐ray fluorescence imaging techniques, we show that the Golgi apparatus is the primary accumulation site for manganese in both neurons and astrocytes, and that manganese targets the neuronal ...
Ines Kelkoul, Aiyarin Kittilukkana, Luis C. C. Huarte, Hiram Castillo‐Michel, Murielle Salome, Stéphane Roudeau, Pauline Belzanne, Matthieu Sainlos, Noémie Pied, Monica Fernandez‐Monreal, Daniel Choquet, Richard Ortega, Asuncion Carmona   +12 more
wiley   +1 more source

Recent Advances on Transition Metal Sulfides for Key Components of Lithium–Sulfur Batteries

Advanced Science
Lithium–sulfur batteries (LSBs), renowned for their cost‐effectiveness and high energy density, stand out as highly promising energy storage solutions with substantial application potential.
Jingxuan Chen, Tingting Sun, Junliang Liu, Hao Yu, Qisheng Zang, Tong Yuan, Fuqin Zhang   +6 more
doaj   +1 more source

Fabrication of NiFe-LDHs Modified Carbon Nanotubes as the High-Performance Sulfur Host for Lithium–Sulfur Batteries

Nanomaterials
Lithium–sulfur batteries offer the potential for significantly higher energy density and cost-effectiveness. However, their progress has been hindered by challenges such as the “shuttle effect” caused by lithium polysulfides and the volume expansion of ...
Lingwei Zhang, Runlan Li, Wenbo Yue
doaj   +1 more source

Optical surface damage from reentrant gases on STS [PDF]

The effect of an ammonia environment on the spectral reflectance of certain optical surfaces in the vacuum ultraviolet region was studied. In particular, the optical surfaces in the space shuttle were considered.
Mcdonald, J. K.
core   +1 more source

Passivation‐Induced Species Dynamics and Microstructural Evolution in Solid‐State Lithium–Sulfur Cathodes

Advanced Science, EarlyView.
The formation of insulating Li2S during discharge in solid‐state lithium–sulfur batteries passivate reaction sites and limits sulfur utilization. In this work, a microstructure‐resolved modeling framework coupling transport and reaction kinetics is developed to predict charge–discharge behavior and reveal particle‐scale species evolution and incomplete
Arpan K. Sharma, Bairav S. Vishnugopi, Elif Pınar Alsaç, Matthew T. McDowell, Partha P. Mukherjee   +4 more
wiley   +1 more source

Advances in High‐Entropy Catalysts for Lithium–Sulfur Batteries: Design Principles, Recent Progress, and Prospects

Advanced Science
Lithium–sulfur (Li–S) batteries are regarded as one of the most promising next‐generation energy storage technologies due to their exceptionally high theoretical energy density, cost‐effectiveness, and environmental sustainability.
Ruohan Hou, Yixin Wei, Jiaxiang Zhang, Jiaying Chen, Shaojie Chen, Shuaiting Sun, Guosheng Shao, Peng Zhang   +7 more
doaj   +1 more source

In situ polymerized quasi-solid polymer electrolytes enabling void-free interfaces for room-temperature sodium–sulfur batteries

Energy Materials and Devices
Rechargeable room-temperature (RT) sodium–sulfur (Na–S) batteries hold great potential for large-scale energy storage owing to their high energy density and low cost.
Jiafang Huang, Zhengguang Song, Junxiong Wu, Yuhui Miao, Manxian Li, Danjing Lin, Kai Zhu, Xiaochuan Chen, Xiaoyan Li, Yuming Chen   +9 more
doaj   +1 more source

Leveraging Macrophage Metabolic Reprogramming for Enhanced Anti‐Tumor Immunity

Advanced Science, EarlyView.
Tumor‐associated macrophages (TAMs) are key regulators of the tumor microenvironment (TME), with their metabolic states playing a critical role in tumor progression or regression. This review summarizes current understanding of TAM metabolic plasticity alongside cutting‐edge bioengineering innovations, outlining a roadmap for transforming the ...
Zhiyun Liu, Lingyao Zeng, Xulin Gan, Yilin Zhou, Han Shen, Dan Wu, Xin Shou, Minmin Jiang, Liyun Shi   +8 more
wiley   +1 more source