Results 161 to 170 of about 16,195 (218)

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad, Pouya Metanat, Michael Thomas, Luke W. Bonham, Tyson Lam, Mehmet Kurt, Hong Nguyen, Tara Ellingson, Mauro Zucchelli, Stefano Casagranda, Quin Lu, Andreas M. Rauschecker, Leo Sugrue, Luis E. Savastano, Christopher P. Hess, Kamalini Ranasinghe, S. Andrew Josephson, Bruce L. Miller, Jennifer S. Yokoyama, Gil D. Rabinovici, Peter A. Ljubenkov, Lawren VandeVrede, Kambiz Nael   +22 more
wiley   +1 more source

Effect of Prechamber Design Parameters on Combustion Characteristics, Emission, and Performance of a Methanol Engine. [PDF]

ACS Omega
Luo J, Liu W, Gong S, Fang Z, Weng W, Gao X.   +5 more
europepmc   +1 more source

Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan, Jordan Safran, Anna Loughman, Grace Lin, Shivanshi Vaid, Dana Allababidi, Peter M. Tessier, Louis T. Dang   +7 more
wiley   +1 more source

Investigation of diesel post injection using diesel/biodisel/methanol/DTBP: a path towards ultra-low smoke emissions and improved fuel economy. [PDF]

Sci Rep
Dave H, Chan CK, Sonawane C, Pandey A, Dixit S.   +4 more
europepmc   +1 more source

Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli, Karine Lacourse, Hélène Blais, Anne‐Sophie Deshaies‐Rugama, Cynthia Thompson, Alex Desautels, Jacques Montplaisir, Milan Nigam, Christophe Moderie, Boshra Khajehpiri, Catherine Duclos, Jean Marc Lina, Julie Carrier, Nadia Gosselin   +13 more
wiley   +1 more source

Effects of Ethanol-Gasoline Blending on Combustion, Performance, and Emissions of a Spark Ignition Engine: An Experimental and Detailed Chemistry-Based Numerical Study. [PDF]

ACS Omega
Khedr AM, Ismael MA, El-Adawy M, Elserfy K, Abdelhafez A, Habib MA, Nemitallah MA.   +6 more
europepmc   +1 more source

Temporal Divergence of True and False Alarms in Pediatric Nocturnal Seizure Monitoring

Annals of Clinical and Translational Neurology, EarlyView.
The early‐morning surge in false seizure alarms supports exploring time‐ or state‐dependent detection thresholds to reduce false detections. ABSTRACT Seizure detection devices can improve the safety of children with epilepsy, yet high false alarms limit their clinical applicability.
Mohammad Shahbakhti, Anemoon T. Bosch, Job van der Palen, Franciscus S. Leijten, Johannes P. van Dijk, Richard H. C. Lazeron, Roland D. Thijs   +6 more
wiley   +1 more source

Online characterisation of oxidative potential and reactive oxygen species of fresh and aged aircraft turbine and ship engine particulate emissions.

Environ Sci Atmos
Barth A, Utinger B, He Q, Paul A, Hartikainen A, Ihalainen M, Etzien U, Piel S, Rohkamp M, Mudan A, Gündling B, Tuuka K, Streibel T, Sklorz M, Czech H, Øvrevik J, Adam T, Hupfer A, Hohaus T, Sippula O, Rudich Y, Buchholz B, Zimmermann R, Kalberer M.   +23 more
europepmc   +1 more source

Towards Sustainable Utilization of Rejuvenated Bitumen: A Review with Emphasis on Secondary Aging, Aging Resistance, and Multiple Rejuvenation. [PDF]

Polymers (Basel)
Zhu H, Guo N, Li Y, Ren S, Wang F, Zhang J, Zheng Z, Su H, Zhao Z, Zhang K.   +9 more
europepmc   +1 more source

Systemic Extracerebral Atherosclerotic Burden and Dementia Risk After Incident Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Stroke survivors are at increased risk of dementia, but clinically accessible markers of risk heterogeneity remain limited. Previous studies have largely examined atherosclerotic disease in individual vascular beds rather than the overall burden of systemic extracerebral atherosclerosis.
Zhexuan Yu, Tianxue Chen, Wei Jin, Weifeng Jin, Haitong Wan   +4 more
wiley   +1 more source