Results 41 to 50 of about 4,709 (183)

An adolescent girl with syndrome of inappropriate antidiuretic hormone secretion preceding the diagnosis of olfactory neuroblastoma – a case report

Frontiers in Endocrinology
ObjectivesWe present an adolescent in whom olfactory neuroblastoma (ONB) was detected on follow-up magnetic resonance imaging (MRI) 2.5 years after SIADH diagnosis.
Sabitha Sasidharan Pillai, Sabitha Sasidharan Pillai, Sabitha Sasidharan Pillai, Jerrold L. Boxerman, Jerrold L. Boxerman, Jan C. Groblewski, Jan C. Groblewski, Bradley D. DeNardo, Bradley D. DeNardo, Mohammed K. Faizan, Mohammed K. Faizan, Lisa Swartz Topor, Lisa Swartz Topor, Renee Robilliard, Renee Robilliard, Monica Serrano-Gonzalez, Monica Serrano-Gonzalez   +16 more
doaj   +1 more source

Functional Olfactory Neuroblastoma Inducing Symptomatic SIADH

Ear, Nose & Throat Journal, 2023
Olfactory neuroblastoma (ONB) is a rare malignancy of the sinonasal cavity, originating from neuroepithelial olfactory cells. Olfactory neuroblastoma can be difficult to diagnose due to its anatomic position and variable symptomatic presentation, leading
Luke Heiland BS, Kurt Heiland MD
doaj   +1 more source

Interplay Between Infectious Diseases and the Endocrine System: An Overview and Clinical Insights

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.
Infectious diseases can disrupt endocrine homeostasis through direct cytopathic injury, autoimmune dysregulation, or pathogen‐derived hormone‐like effects. Viruses and bacteria are the most frequent agents, whereas fungi and parasites contribute less commonly, even remaining clinically relevant, especially in the immunocompromised population.
Francesco Capoccia, Valentina D'Onghia, Valentina Semeraro, Esposito Susanna, Maria Elisabeth Street   +4 more
wiley   +1 more source

What Matters Most: A Case of Pemphigus Vulgaris in a Nonagenarian Physician

Journal of the American Geriatrics Society, EarlyView.
Svetlana Bagdasarov, Loma Dave, Alan Sang, Lisa Zhou, Billie Fyfe‐Kirschner, Ying Guo, Ibiyonu Lawrence   +6 more
wiley   +1 more source

Antidepressants and the risk of hyponatremia: A multi‐institutional cohort study using observational medical outcomes partnership—Common Data Model

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1706-1715, June 2026.
Aim Hyponatremia is a common yet potentially serious adverse event associated with antidepressants. Identifying the antidepressant class with the least risk of hyponatremia would improve patient safety. Methods Using electronic medical records from 15 hospitals standardized into Observational Medical Outcomes Partnership Common Data Model (2003–2023 ...
Kyungyeon Jung, Ju Hwan Kim, Da Eun Hyeon, Jeongmoon Ji, Min Young Lee, Hayun Choi, Dong Yun Lee, Min Woo Kim, Yoonmin Jang, Seonghoon Hwang, Jaehyeong Cho, Seok Young Song, Sang Youl Rhee, Jae Myung Cha, Won‐Woo Seo, Chang‐Won Jeong, Seung‐Jin Kwag, Woo Jin Kim, Jaeuk Hwang, Min‐ho Kim, Rae Woong Park, Ju‐Young Shin   +21 more
wiley   +1 more source

Ectopic Olfactory Neuroblastoma of the Maxillary Sinus: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Olfactory neuroblastoma is a rare neuroendocrine tumor typically arising from the superior nasal cavity, and primary occurrence in the maxillary sinus is exceptionally uncommon, often leading to diagnostic confusion with other sinonasal malignancies. A 34‐year‐old man presented with bilateral nasal obstruction, recurrent epistaxis, and frontal
Hesam Jahandideh, Farzad Yadmehr, Mehdi Abrishami   +2 more
wiley   +1 more source

More Than a Question of Correlation: Characterization of the Evidentiary Basis for Biomarker Surrogates Used in European Marketing Authorizations

Clinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1522-1536, June 2026.
Traditionally, clinical outcomes measuring how a patient feels, functions, or survives are preferred endpoints in clinical trials; however, some may take a long time to manifest in slowly developing diseases. Biomarkers, if properly validated, can serve as surrogate endpoints, acting as substitutes for clinical outcomes.
Renske Johanna Grupstra, Viktoriia Starokozhko, Elisabeth Bakker, Anna Maria Gerdina Pasmooij, Peter Gerardus Maria Mol   +4 more
wiley   +1 more source

Efficacy of MAPK inhibitors in children with neurodegenerative Langerhans cell histiocytosis: Results from the European Consortium for Histiocytosis

HemaSphere, Volume 10, Issue 6, June 2026.
Abstract Neurodegenerative Langerhans cell histiocytosis (ND‐LCH) is a severe and debilitating complication of LCH with no effective treatment. In this study, we assessed the efficacy of MAPK inhibitors (MAPKi) in a large cohort of children with ND‐LCH. We included pediatric patients with ND‐LCH who received MAPKi between 2013 and 2025.
Francesco Pegoraro, Francois Chalard, Dmitry Evseev, Mohamed Barkaoui, Solenne Le Louet, Julian Thalhammer, Nathalie Aladjidi, Alexandra Salmon, Perrine Marec‐Berard, Stefania Gaspari, Carmela De Fusco, Irene Trambusti, Antonio Verrico, Anna Raciborska, Karel Svojgr, Zdenka Křenová, Olga Slater, Gerard Millen, Myriam Ben Arush, Dana Ashkenazi Lustig, Tatiana Von Bahr Greenwood, Caroline Hutter, Itziar Astigarraga, Mónica López‐Duarte, Lorena Valero‐Arrese, María José Ortega Acosta, Cor van den Bos, Leonie Naeije, Daniel Martin‐Munoz, Anna Perrone, Marzia Mortilla, Olivier Felician, Ahmed Idbaih, Sébastien Héritier, Vasanta Nanduri, Milen Minkov, Jan‐Inge Henter, Elena Sieni, Jean Donadieu   +38 more
wiley   +1 more source

An Atypical Presentation of Tuberculous Ascites, Severe Hyponatremia, and Acute Kidney Injury in a Young Male

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT A 25‐year‐old male who had been in good health before presenting with right lower lobe pneumonia, severe hyponatremia (Na 117 mEq/L), distension, and reduced urine output. AKI secondary to acute glomerulonephritis (GN) or interstitial nephritis was suggested by the initial workup. He was discharged for outpatient nephrology follow‐up following
Bassem Al Hariri, Muhammad Sharif, Memon Noor Illahi, Asgad Mohamed Ahmed Eltigani, Usamah Saad Mohammad Al Anbagi, Muayad Ahmad   +5 more
wiley   +1 more source

Duloxetine‐induced syndrome of inappropriate antidiuretic hormone secretion in a patient with neuropathic pain

Clinical Case Reports
Key Clinical Message Syndrome of inappropriate antidiuretic hormone secretion (SIADH) induces hyponatremia accompanied by uric acid reduction. We report a case of a patient with small‐cell lung cancer who developed SIADH with hypouricemia after ...
Nobuyuki Takahashi, Yukiko Mori, Kenji Momo, Hidetomo Murakami, Hironori Tanaka   +4 more
doaj   +1 more source