Results 71 to 80 of about 6,337 (212)

Duloxetine‐induced syndrome of inappropriate antidiuretic hormone secretion in a patient with neuropathic pain

Clinical Case Reports
Key Clinical Message Syndrome of inappropriate antidiuretic hormone secretion (SIADH) induces hyponatremia accompanied by uric acid reduction. We report a case of a patient with small‐cell lung cancer who developed SIADH with hypouricemia after ...
Nobuyuki Takahashi, Yukiko Mori, Kenji Momo, Hidetomo Murakami, Hironori Tanaka   +4 more
doaj   +1 more source

More Than a Question of Correlation: Characterization of the Evidentiary Basis for Biomarker Surrogates Used in European Marketing Authorizations

Clinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1522-1536, June 2026.
Traditionally, clinical outcomes measuring how a patient feels, functions, or survives are preferred endpoints in clinical trials; however, some may take a long time to manifest in slowly developing diseases. Biomarkers, if properly validated, can serve as surrogate endpoints, acting as substitutes for clinical outcomes.
Renske Johanna Grupstra, Viktoriia Starokozhko, Elisabeth Bakker, Anna Maria Gerdina Pasmooij, Peter Gerardus Maria Mol   +4 more
wiley   +1 more source

SIADH following laparoscopic cholecystectomy [PDF]

Canadian Journal of Anaesthesia, 1998
To present an unusual case of inappropriate antidiuretic hormone secretion syndrome after a minor surgical procedure in a healthy patient.A 71-yr-old woman underwent uneventful laparoscopic cholecystectomy for gallstones under general anaesthesia. Fifty-two hours post operatively she began convulsing and was found to have a serum sodium concentration ...
openaire   +2 more sources

SIADH-associated hyponatremia in hospitalized COVID-19 patients: relationship with ınflammatory and stress response markers

Aims: Hyponatremia observed during the course of COVID-19 infection is closely associated with disease prognosis. The objective of this study is to determine the prevalence of Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) in patients ...
Murat Alay, Okan Özgökçe
core   +1 more source

Paciente oncológico y SIADH [PDF]

The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a condition characterized by elevated secretion of vasopressin and presents with hyponatremia, low plasma osmolality, inappropriately high urine osmolality, and elevated natriuresis.
Dulcey-Hormiga, Isabel Cristina, Monzón-Camps, Helena, Jiménez-Maurí, Anna   +2 more
core   +1 more source

A Diagnostic Odyssey: Post-Surgical Polyuria and Hyponatremia Unmasking Multiple Myeloma-Associated SIADH-A Case Report [PDF]

Liaquat National Journal of Cancer Care
Hyponatremia and polyuria are common postoperative complications, often posing significant diagnostic challenges. This case report details a complex scenario of a 56-year-old male with hypertension and diabetes who developed polyuria post-femur cyst ...
Shayan Ali Qazi
doaj   +1 more source

Efficacy of MAPK inhibitors in children with neurodegenerative Langerhans cell histiocytosis: Results from the European Consortium for Histiocytosis

HemaSphere, Volume 10, Issue 6, June 2026.
Abstract Neurodegenerative Langerhans cell histiocytosis (ND‐LCH) is a severe and debilitating complication of LCH with no effective treatment. In this study, we assessed the efficacy of MAPK inhibitors (MAPKi) in a large cohort of children with ND‐LCH. We included pediatric patients with ND‐LCH who received MAPKi between 2013 and 2025.
Francesco Pegoraro, Francois Chalard, Dmitry Evseev, Mohamed Barkaoui, Solenne Le Louet, Julian Thalhammer, Nathalie Aladjidi, Alexandra Salmon, Perrine Marec‐Berard, Stefania Gaspari, Carmela De Fusco, Irene Trambusti, Antonio Verrico, Anna Raciborska, Karel Svojgr, Zdenka Křenová, Olga Slater, Gerard Millen, Myriam Ben Arush, Dana Ashkenazi Lustig, Tatiana Von Bahr Greenwood, Caroline Hutter, Itziar Astigarraga, Mónica López‐Duarte, Lorena Valero‐Arrese, María José Ortega Acosta, Cor van den Bos, Leonie Naeije, Daniel Martin‐Munoz, Anna Perrone, Marzia Mortilla, Olivier Felician, Ahmed Idbaih, Sébastien Héritier, Vasanta Nanduri, Milen Minkov, Jan‐Inge Henter, Elena Sieni, Jean Donadieu   +38 more
wiley   +1 more source

Syndrome de sécrétion inappropriée d'hormone antidiurétique secondaire à la rispéridone et la carbamazépine: à propos d'un cas

The Pan African Medical Journal, 2019
Le syndrome de sécrétion inappropriée de l'hormone antidiurétique (SIADH) représenterait environ 50% de tous les cas diagnostiqués d'hyponatrémie. Seule une faible proportion de SIADH serait d'origine médicamenteuse. Nous rapportons le cas d'une patiente
Assia Fadili, Nadia Attouche, Boubaker Charra, Khadija Mchichi Alami, Mohamed Agoub   +4 more
doaj   +1 more source

Idiopathic SIADH in young patients: don't forget the nose [PDF]

, 2017
Olfactory neuroblastoma (ONB) is an uncommon neuroendocrine sinonasal cancer associated by many authors to ectopic production of several biologically active substances. We report a case of a 31-year-old male patient who presented with idiopathic syndrome
D. Lucidi, Colosimo, C., Bastanza, G., Parrilla, C., Lucidi, D., C. Colosimo, G. Bastanza, Petrone, G., C. Parrilla, G. Petrone, Lucidi D, Colosimo C, Parrilla C, Petrone G, Bastanza G   +14 more
core   +2 more sources

Downward resetting of the osmotic threshold for thirst in patients with SIADH

The syndrome of inappropriate antidiuretic hormone (SIADH) is characterized by euvolemic hyponatremia. Patients with SIADH continue to drink normal amounts of fluid, despite plasma osmolalities well below the physiological osmotic threshold for onset of ...
Moore K, Thompson CJ, Smith D, Baylis PH, Tormey W   +4 more
core   +3 more sources