Results 121 to 130 of about 6,019,441 (302)
Simulations of Antigenic Variability in Influenza A [PDF]
, 2008 Computational models of the immune system (IS) and pathogenic agents have several applications, such as theory testing and validation, or as a complement to first stages of drug trials.
Agostinho C. Rosa +2 more
core +1 more source
BMEMat, EarlyView.A multifunctional nanomedicine is designed to engineer NK cells for enhanced cancer immunotherapy through perforation and desialylation, enabling real‐time monitoring of ATP and GrB levels for precise efficacy assessment. Abstract Efficient enhanced NK cell therapy is of critical importance in the immune treatment of cancer.
Yuanjiao Yang +8 more
wiley +1 more source
Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite
Nature Communications, 2016 Plasmodium knowlesi is a zoonotic parasite transmitted from macaques causing malaria in humans in Southeast Asia. Plasmodium parasites bind to red blood cell (RBC) surface receptors, many of which are sialylated. While macaques synthesize the sialic acid
Selasi Dankwa +10 more
semanticscholar +1 more source
ChemFoodChem, EarlyView.This work presents a pH‐responsive ON–OFF fluorescent system based on a novel pyranoflavylium dye functionalized with a boronic acid receptor. The receptor exhibits a markedly higher affinity for the catechol‐containing polyphenol (+)‐catechin than for conventional diol‐rich molecules such as glucose and lactic acid.
Beatriz Senra +5 more
wiley +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1398-1415, April 2025.Abstract Background Cardiac remodelling, a crucial aspect of heart failure, is commonly investigated in preclinical models by quantifying cardiomyocyte cross‐sectional area (CSA) and microvascular density (MVD) via histological methods, such as immunohistochemistry.
Tamás G. Gergely +14 more
wiley +1 more source
Diagnostic Value of Sialic Acid in Pleural Effusion
Chinese Journal of Lung Cancer, 2010 The present study was conducted in 30 patients of malignant pleural effusion and 30 patients of non malignant pleural effusion. Pleural fluid and blood samples were taken at the time of admission, before starting any treatment.
S KHARB, S TANDON, A BANSAL
doaj
ELECTROPHORESIS, EarlyView.This study improved an HPLC–UV method for quantifying 3‐O‐methylquercetin in porcine nasal mucosa following ICH M10 and ANVISA (Brazil) guidelines, assessing selectivity, linearity, accuracy, precision, and robustness. The method was applied for the first time to evaluate release, permeation, and retention profiles of a nasal formulation.
Jeniffer Viviana Ramirez Hernández +6 more
wiley +1 more source
Sialic acid catabolism drives intestinal inflammation and microbial dysbiosis in mice
Nature Communications, 2015 Rapid shifts in microbial composition frequently occur during intestinal inflammation, but the mechanisms underlying such changes remain elusive. Here we demonstrate that an increased caecal sialidase activity is critical in conferring a growth advantage
Yen-Lin Huang +4 more
semanticscholar +1 more source
WONOEP XVII appraisal: The role of the extracellular matrix in epilepsy
Epilepsia, EarlyView.Abstract The extracellular matrix (ECM) is composed of proteoglycans and glycoproteins that regulate the external environment surrounding neurons, glia, and the vascular system. The ECM is vital for maintaining the structure and function of the brain and also acts as a reservoir for various signaling molecules and neurotransmitters, modulating synaptic
Eleonora Lugara +7 more
wiley +1 more source
Sialic acid-dependent cell entry of human enterovirus D68
Nature Communications, 2015 Human enterovirus D68 (EV-D68) is a causative agent of childhood respiratory diseases and has now emerged as a global public health threat. Nevertheless, knowledge of the tissue tropism and pathogenesis of EV-D68 has been hindered by a lack of studies on
Yue Liu +7 more
semanticscholar +1 more source