Results 141 to 150 of about 5,135,061 (391)
Metal‐Mediated Protein Engineering within Live Cells
Chemistry – An Asian Journal, Volume 20, Issue 6, March 17, 2025.This review discusses how metal ions can mediate protein modification within live cells. With its easy handling, rapid solubility, and ease of internalization within the cells, metal ions can be an excellent stimulus for many organic reactions needed within an intracellular medium, which can modify proteins and lead to applications in chemistry ...
Pritam Ghosh
wiley +1 more source
Genetic Divergence and Antibody Expression Influence the N‐Glycomes of CHO‐K1 and CHO‐S Cells
Biotechnology and Bioengineering, EarlyView.ABSTRACT While Chinese hamster ovary (CHO) cells continue to be the workhorse of recombinant therapeutic protein production, decades of genetic divergence in the industrially relevant CHO‐K1 and CHO‐S cell lines, are likely to have resulted in differing glycosylation capabilities. Glycosylation can influence the efficacy, serum half‐life, and safety of
Roberto Donini +6 more
wiley +1 more source
Isolation of Sialic Acid from Brain Gangliosides. [PDF]
, 1955 Lars Svennerholm +3 more
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Engineering antibodies with cancer‐associated binding sites
BMEMat, EarlyView.This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian +4 more
wiley +1 more source
Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017 The objective of this study is to evaluate plasma levels of total Sialic acid TSA and Lipid –associated Sialic acid LSA as a marker of Rheumatoid Arthritis AR. Plasma Sialic acid is known as a parameter of inflammation. In the present study, in order
N. S. Hamad
doaj
Isolation of Sialic Acid from Gangliosides. [PDF]
, 1955 Gunnar Blix, Lars Odin
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Harnessing chimeric antigen receptor macrophages against solid tumors
Cancer Communications, EarlyView.Abstract Macrophages are prevalent in multiple tumors and exhibit diverse and potent functional activities. Therapeutic reprogramming of macrophage phenotypes represents a promising strategy for cancer immunotherapy. Engineering chimeric antigen receptors (CARs) to endow macrophages with anti‐tumor capacities demonstrated encouraging efficacy ...
Mengru Wang +3 more
wiley +1 more source
Beyond FimH: Diversity and Relevance of Carbohydrate‐Binding Fimbrial Proteins in Escherichia coli
ChemBioChem, EarlyView.This review discusses fimbrial lectins found in Escherichia coli (E. coli) other than FimH, which could be targeted to treat E. coli pathogenicity as an alternative to antibiotic treatment. Escherichia coli (E. coli) is responsible for multiple diseases in humans and animals.
Oliwier R. Dulawa +3 more
wiley +1 more source
Cell Biology International, EarlyView.ABSTRACT Chagas disease, caused by the protozoan Trypanosoma cruzi, is a neglected tropical disease with limited treatment options and no available vaccine. Understanding the role of proteins in the parasite's biological cycle is critical for advancing vaccine development and optimizing therapies.
Normanda Souza‐Melo +2 more
wiley +1 more source
STUDIES OF SIALIC ACID-CONTAINING MUCINS IN BOVINE SUBMAXILLARY AND RAT SUBLINGUAL GLANDS [PDF]
, 1961 G. Quintarelli +4 more
openalex +1 more source