Results 151 to 160 of about 113,461 (351)
PROTEOMICS, EarlyView.ABSTRACT Mass spectrometry (MS) offers robust, label‐free approaches for characterizing ligand–protein interactions through two main strategies: affinity‐based and stability‐based assays. However, their application to membrane proteins (MPs)—a major class of drug targets—has been limited by challenges such as structural complexity, low native ...
Jonathon C. Lambos +3 more
wiley +1 more source
Increased Serum Sialic Acids in Depression.
مجلة كلية الطب, 2007 Background: Total serum sialic acid (TSA) and lipid associated sialic acid (LSA) have not been measured yet in depressive disorders. Aim :The present study was undertaken to show if there is any change in the concentration of different forms of sialic ...
Hussein Kadhem Abdul Hussein +2 more
doaj
The Thiobarbituric Acid Assay of Sialic Acids
Journal of Biological Chemistry, 1959 Publisher Summary This chapter discusses the different aspects of thiobarbituric acid assay of sialic acid. Periodate oxidation of the neuraminic acid backbone of sialic acids results in the formation of β -formylpyruvic acid from carbon atoms 1 to 4.
openaire +3 more sources
Synergies in Self‐Assembly—From Supramolecular Polymers to Defined Hierarchical Superstructures
Journal of Polymer Science, EarlyView.Shaping supramolecular polymers built from molecular building blocks into superstructures with defined dimensions. Synergies within supramolecular architectures such as chirality or an additional second orthogonal driving force that does not interfere with the central supramolecular motif facilitate the confinement of the growth of these ...
Klaus Kreger +2 more
wiley +1 more source
Evaluation of L-fucose and Sialic Acid Levels in Patients With Colorectal Cancer and Control Subject
Research in Molecular Medicine, 2020 Background: Currently, glycans, which are known as functional molecules in the biological system, are being under study as potential cancer markers. This study aimed to determine the level of serum L-fucose and sialic acid as the biomarkers in patients ...
Roya Abbasinatajomrani +3 more
doaj
Small, EarlyView.Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti +5 more
wiley +1 more source
Partial characterization of the sialic acid-free forms of α1-acid glycoprotein from human plasma [PDF]
, 1967 Karl Schmid +4 more
openalex +1 more source
Biomaterial‐Based Emergency Intervention for Secondary Spinal Cord Injury
Small Science, EarlyView.Emergency intervention using advanced biomaterials targets key pathological mechanisms to block secondary spinal cord injury (SCI) by inhibiting inflammation, reducing excitotoxicity, restoring the blood−spinal cord barrier, and limiting scar formation, which provides significant neural protection and promotes neural regeneration, offering promising ...
Jincheng Li +5 more
wiley +1 more source
Small Methods, EarlyView.The schematic illustrates a workflow showing the current investigation using a boronic acid‐functionalized core–shell mesoporous silica‐TiO₂ (CSMS@TiO₂‐GLYMO‐APB) for N‐glycopeptide enrichment from biological samples, involving trypsin digestion, enrichment, deglycosylation with PNGase F, and subsequent mass spectrometry (MALDI‐TOF MS and Nano‐LC‐MS/MS)
Mohamed Adly Gab‐Allah +8 more
wiley +1 more source