Results 131 to 140 of about 648,970 (354)

Delivery of Islatravir via High Drug‐Load, Long‐acting Microarray Patches for the Prevention or Treatment of Human Immunodeficiency Virus

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Islatravir‐loaded dissolving microarray patches (MAPs) provide a minimally invasive, long‐acting solution for HIV‐1 prevention and treatment. In rats, sustained islatravir delivery lasts up to three months, while in minipigs, efficacious plasma levels are detected for six days.
Qonita Kurnia Anjani   +11 more
wiley   +1 more source

Healthy Workers, Healthy Businesses: A Small Business Analysis of Earned Paid Sick Time in New York City [PDF]

open access: yes, 2012
This report examines small business considerations in relation to New York City's earned paid sick time proposal. It combines data from a review of existing research on the costs and benefits of a paid sick leave policy with statements from local small ...

core  

Reservoir‐Type Subcutaneous Implantable Devices Containing Porous Rate Controlling Membranes for Sustained Delivery of Risperidone

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a novel implantable drug delivery systemwith a biodegradable poly(caprolactone) membrane and compressed drug core forsustained release. These implantable devices deliver risperidone in vitro for 170 days and in vivo for 49 days in rats, showing promise for chronic conditions like schizophrenia.
Linlin Li   +9 more
wiley   +1 more source

CLDN18.2 CAR‐derived Extracellular Vesicle Immunotherapy Improves Outcome in Murine Pancreatic Cancer

open access: yesAdvanced Healthcare Materials, EarlyView.
CLDN18.2 CAR‐T cell‐derived small extracellular vesicles (CAR‐sEVs) display potent cytotoxicity and prolong survival in preclinical pancreatic cancer models. They contain functional CAR proteins and granzyme B, exhibit antigen specificity, and effectively target tumor cells while sparing healthy cells.
Yue Qing   +7 more
wiley   +1 more source

Prevalence of, and factors associated with, long-term COVID-19 sick leave in working-age patients followed in general practices in Germany

open access: yesInternational Journal of Infectious Diseases, 2021
Objectives: To investigate the prevalence of, and the factors associated with, long-term sick leave in working-age patients diagnosed with COVID-19 in general practices in Germany. Methods: Patients aged 18–65 years diagnosed with COVID-19 in any of 1255
Louis Jacob, MD-PhD   +6 more
doaj  

Intergenerational transmission of long-term sick leave [PDF]

open access: yes, 2013
The aim of this study is to investigate the importance of intergenerational transmission of sick leave using universal Swedish register data on the rate of sickness benefits.
Josephson, Malin   +3 more
core  

Is Part-Time Sick Leave Helping the Unemployed? [PDF]

open access: yesSSRN Electronic Journal, 2011
Using a discrete choice one-factor model, we estimate mean treatment parameters and distributional treatment parameters to analyze the effects of degree of sick leave on the probability of full recovery of lost work capacity for employed and unemployed individuals, respectively. Our results indicate that one year after the sick leave spell started, the
openaire   +5 more sources

Albumin Corona Overturns Long‐Acting Behaviors of Myristic Acid‐Conjugated Quetiapine Nanosuspension

open access: yesAdvanced Healthcare Materials, EarlyView.
Albumin corona alters surface properties and enhances colloidal stability by overturning pH responsiveness and nano‐aggregation behaviors of long‐acting myristic acid‐conjugated quetiapine nanosuspensions (QMN), resulting in accelerated in vitro and in vivo drug release.
Hy Dinh Nguyen   +2 more
wiley   +1 more source

A prediction rule for shoulder pain related sick leave: a prospective cohort study

open access: yesBMC Musculoskeletal Disorders, 2006
Background Shoulder pain is common in primary care, and has an unfavourable outcome in many patients. Information about predictors of shoulder pain related sick leave in workers is scarce and inconsistent.
van der Heijden Geert JMG   +5 more
doaj   +1 more source

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