Results 201 to 210 of about 22,367,796 (324)

Stress Hyperglycemia Drives CD4+ T Cell PANoptosis and Postoperative Organ Injury via Monocyte‐Derived Succinate

Advanced Science, EarlyView.
High glucose is linked to reduced succinate dehydrogenase activity in CD14+ monocytes, accompanied by succinate accumulation and extracellular release. Extracellular succinate exacerbates mitochondrial ROS production and mtDNA release in CD4+ T cells. Cytosolic mtDNA then activates Z‐DNA binding protein 1 (ZBP1) and engages ZBP1‐associated inflammatory
Shuai Zhao, Xuemei Miao, Wei Luo, Tao Liu, Yang Wang, Jiaying Li, Di Fu, Weiyun Shen, Yan Luo, Kang Chen, Ruping Dai, Hui Li   +11 more
wiley   +1 more source

Voice Changes Related to Perceived Indoor Air Quality in Finnish Teachers: A Proof-of-Concept Field Study. [PDF]

Int J Environ Res Public Health
Vertanen-Greis H, Häkkilä S, Löyttyniemi E, Vintturi J, Maalouf A, Geneid A.   +5 more
europepmc   +1 more source

DDX3x Regulates NINJ1 Transcription via Histone Lactylation in Sepsis Associated‐Acute Kidney Injury

Advanced Science, EarlyView.
This study identifies a potential therapeutic approach for sepsis‐associated acute kidney injury (SA‐AKI). We found that during SA‐AKI, reduced expression of DDX3x in renal tubular epithelial cells mediates histone delactylation, which in turn upregulates NINJ1 transcription and triggers tubular cell death. Conversely, Odetiglucan confers protection by
Hongyu Liang, Jihong Jiang, Huanxin Yin, Chunyan Liu, Hongjun Huang, Yan Luo, Minmin Zhu, Qiuyun Wang   +7 more
wiley   +1 more source

Work-Related Illnesses and Work Disability in Brazil: A Scoping Review of the Epidemiological Profile and Determinants of Sick Leave and Occupational Accidents. [PDF]

Epidemiologia (Basel)
Lourenção LG, Medeiros LSP.
europepmc   +1 more source

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

Advanced Science, EarlyView.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie, Zheyu Zhang, Hao Zhang, Linke Bian, Penglong Zheng, Sijia Zhou, Minqi Wang, Mingyu Qu, Yufei Wang, Xinhua Qu, Bing Yue   +10 more
wiley   +1 more source

Stakeholder Perspectives on Cancer Survivors' Return to Work and Well-Being: Qualitative Interview Study. [PDF]

JMIR Cancer
Fällman SL, Wijk K, Efverman A, Eklund L, Fessé P, Trygged S, Fjell M.   +6 more
europepmc   +1 more source

Deciphering the Crystallinity‐Dependent Sensitivity of Charge Injection in n‐Channel Organic Transistors: Reliable Characterization and Optimized Performance

Advanced Science, EarlyView.
Precise characterization of n‐type organic semiconductors necessitates decoupling interfacial constraints from intrinsic charge transport. This work reveals that disordered polymers are particularly vulnerable to contact‐limited bottlenecks compared to their crystalline counterparts.
Walid Boukhili, Chan Zhang, Jianeng Ma, Changwoo Yu, Chee Leong Tan, Huabin Sun, Zhihao Yu, Guangan Yang, Xiang Wan, Li Zhu, Yong Xu, Liyang Yu, Ruipeng Li, Seung‐Hoon Lee, Zhuping Fei, Dongyoon Khim   +15 more
wiley   +1 more source

Prolonged Hospitalisation After Lung Cancer Surgery: A Qualitative Study of Patient Experiences of the Reasons for Their Extended Stay. [PDF]

Nurs Res Pract
Donsel PO, Missel M.
europepmc   +1 more source

Factors Related to Knowledge, Health Belief and Sick Role Behavior to the Coronary Artery Disease among Patients with Coronary Artery Disease

, 2011
Young-Ok Kang, Young-Chae Cho
semanticscholar   +1 more source

Neuromorphic Optical Tracking and Imaging of Randomly Moving Targets Through Dynamic Dense Scattering Media

Advanced Science, EarlyView.
Vision begins not with images but with change: the retina fires only when something moves, handing the brain a stream of spikes. A neuromorphic imaging system adopts the same strategy—an event sensor that sees like the retina, a spiking network that thinks like the brain—to track and reconstruct fully randomly moving targets through tissue (phantom ...
Ning Zhang, Arto Nurmikko
wiley   +1 more source