Results 251 to 260 of about 105,245 (307)

First Antibiotic Prophylaxis Prescription Among Children With Sickle Cell Disease.

open access: yesJAMA Pediatr
Shi JS   +6 more
europepmc   +1 more source
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Variability in sickle cell knowledge by sickle cell status

Journal of Genetic Counseling, 2023
AbstractDisease‐specific knowledge allows individuals with sickle cell disease, sickle cell trait, and unaffected family members alike to make informed decisions and support those affected by the condition. The current study assesses how sickle cell knowledge varies by disease status within families affected by sickle cell disease.
Fiona Gilpin‐Macfoy   +2 more
openaire   +2 more sources

The nephropathy of sickle cell trait and sickle cell disease

Nature Reviews Nephrology, 2022
Sickle cell syndromes, including sickle cell disease (SCD) and sickle cell trait, are associated with multiple kidney abnormalities. Young patients with SCD have elevated effective renal plasma flow and glomerular filtration rates, which decrease to normal ranges in young adulthood and subnormal levels with advancing age.
Kenneth I. Ataga   +2 more
openaire   +2 more sources

Sickle cell disease [PDF]

open access: yesNature Reviews Disease Primers, 2018
Sickle cell disease (SCD) is a group of inherited disorders caused by mutations in HBB, which encodes haemoglobin subunit β. The incidence is estimated to be between 300,000 and 400,000 neonates globally each year, the majority in sub-Saharan Africa. Haemoglobin molecules that include mutant sickle β-globin subunits can polymerize; erythrocytes that ...
Gregory J Kato   +2 more
exaly   +8 more sources

SICKLE CELL

Clinics in Perinatology, 2001
The initiation of newborn screening and its virtually universal implementation will eventually yield a population in which sickle cell disease has been identified and comprehensive care is provided for children. The situation with SCT is different; there will continue to be the identification of parents who have the potential for having a child with a ...
C F, Whitten, W, Whitten-Shurney
openaire   +2 more sources

Sickle-cell trait and sickle-cell anaemia

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1951
Abstract (1) If sickle-cell trait is regarded as a heterozygous condition (Ss) and sickle-cell anaemia as a homozygous state (SS), then sickle-cell anaemia can only arise as a result of the mating of two heterozygous individuals (Ss x Ss), or the mating of a heterozygous and a homozygous (Ss x SS) or of two homozygous (SS x SS). 1.
H, FOY, A, KONDI, C, ALEXANDRIDES
openaire   +2 more sources

The Rate of Sickling of Cells Containing Sickle-Cell Haemoglobin

Clinical Science, 1973
1. A rapid-reaction apparatus was used to measure the rate at which cells containing sickle-cell haemoglobin (HbS) undergo morphological changes as a result of very rapid deoxygenation. The events occurring under these circumstances were found to take place in two stages. 2.
M W, Rampling, J A, Sirs
openaire   +2 more sources

Sickle Cell Nephropathy

Annals of Internal Medicine, 1970
Excerpt Patients with sickle-cell anemia have a defect in renal concentrating ability. This abnormality has been characterized functionally as an inability to attain normal maximum osmolality level...
openaire   +2 more sources

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