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Annual Review of Biomedical Engineering, 2010
As the predominant cell type in blood, red blood cells (RBCs) and their biomechanical properties largely determine the rheological and hemodynamic behavior of blood in normal and disease states. In sickle cell disease (SCD), mechanically fragile, poorly deformable RBCs contribute to impaired blood flow and other pathophysiological aspects of the ...
Gilda A, Barabino +2 more
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As the predominant cell type in blood, red blood cells (RBCs) and their biomechanical properties largely determine the rheological and hemodynamic behavior of blood in normal and disease states. In sickle cell disease (SCD), mechanically fragile, poorly deformable RBCs contribute to impaired blood flow and other pathophysiological aspects of the ...
Gilda A, Barabino +2 more
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A Review of Automated Methods for the Detection of Sickle Cell Disease
IEEE Reviews in Biomedical Engineering, 2020Detection of sickle cell disease is a crucial job in medical image analysis. It emphasizes elaborate analysis of proper disease diagnosis after accurate detection followed by a classification of irregularities, which plays a vital role in the sickle cell
P. Das +3 more
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American Journal of Diseases of Children, 1923
J. B. Herrick, 1 in 1910, reported a peculiar dyscrasia characterized by severe anemia, with the occurrence in the blood of elongated and sickle-shaped erythrocytes. Three instances of this condition have since been described, one by R. E. Washburn; 2 one by Cook and Myer, 3 and one by V. R. Mason. 4 Emmel 5 further studied the blood of Cook and Myer's
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J. B. Herrick, 1 in 1910, reported a peculiar dyscrasia characterized by severe anemia, with the occurrence in the blood of elongated and sickle-shaped erythrocytes. Three instances of this condition have since been described, one by R. E. Washburn; 2 one by Cook and Myer, 3 and one by V. R. Mason. 4 Emmel 5 further studied the blood of Cook and Myer's
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Southern Medical Journal, 1977
Hepatic dysfunction is a common finding in patients with sickle cell disease but viral hepatitis appears to be an unusual complication in the adult SS patient. Only five cases of viral hepatitis were recorded in 378 admissions for SS crisis. In contrast, hepatic crisis occurred as a distinct event in 9% of 88 patients with sickle cell anemia.
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Hepatic dysfunction is a common finding in patients with sickle cell disease but viral hepatitis appears to be an unusual complication in the adult SS patient. Only five cases of viral hepatitis were recorded in 378 admissions for SS crisis. In contrast, hepatic crisis occurred as a distinct event in 9% of 88 patients with sickle cell anemia.
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JAMA: The Journal of the American Medical Association, 1974
IT IS fitting that the shape of a sickled red blood cell (RBC) should resemble that of a kidney. The patient with sickle cell trait or disease is liable to experience several types of sickle cell nephropathy. The best known of these is gross hematuria, seen most often with the trait.
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IT IS fitting that the shape of a sickled red blood cell (RBC) should resemble that of a kidney. The patient with sickle cell trait or disease is liable to experience several types of sickle cell nephropathy. The best known of these is gross hematuria, seen most often with the trait.
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Issues in Comprehensive Pediatric Nursing, 1980
Sickle-cell anemia is a genetic disorder characterized by abnormal hemoglobin. One out of every 500 black children in the United States is affected by this disease. Eight to ten percent of the black population has the sickle-cell trait. While other hemoglobinopathies have been identified that also produce erythrocyte sickling and destruction, the ...
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Sickle-cell anemia is a genetic disorder characterized by abnormal hemoglobin. One out of every 500 black children in the United States is affected by this disease. Eight to ten percent of the black population has the sickle-cell trait. While other hemoglobinopathies have been identified that also produce erythrocyte sickling and destruction, the ...
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Annals of Internal Medicine, 1978
Excerpt To the editor: The "natural history" of sickle cell anemia in Saudi Arabs (Ann Intern Med88:1-6, 1978) is certainly different from the disease as we see it in the United States but not as d...
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Excerpt To the editor: The "natural history" of sickle cell anemia in Saudi Arabs (Ann Intern Med88:1-6, 1978) is certainly different from the disease as we see it in the United States but not as d...
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2020
Sickle cell hemoglobin (HbS) is an example of a genetic variant of human hemoglobin where a point mutation in the β globin gene results in substitution of glutamic acid to valine at sixth position of the β globin chain. Association between tetrameric hemoglobin molecules through noncovalent interactions between side chain residue of βVal6 and ...
Amit Kumar, Mandal +2 more
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Sickle cell hemoglobin (HbS) is an example of a genetic variant of human hemoglobin where a point mutation in the β globin gene results in substitution of glutamic acid to valine at sixth position of the β globin chain. Association between tetrameric hemoglobin molecules through noncovalent interactions between side chain residue of βVal6 and ...
Amit Kumar, Mandal +2 more
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JAMA: The Journal of the American Medical Association, 1974
THE assertion of black pride and aspiration has produced painful as well as happy readjustments: bloody civil strife together with burgeoning civil rights; abject mea culpa from some, abuse of the mea culpists by others; imposition of quotas welcomed today, to become cursed tomorrow.
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THE assertion of black pride and aspiration has produced painful as well as happy readjustments: bloody civil strife together with burgeoning civil rights; abject mea culpa from some, abuse of the mea culpists by others; imposition of quotas welcomed today, to become cursed tomorrow.
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Sickle Cell Disease: A Review.
Journal of the American Medical Association (JAMA), 2022P. Kavanagh, Titilope A Fasipe, T. Wun
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