Results 111 to 120 of about 247,564 (312)

A study of 28 pregnant women with sickle cell disease and COVID-19: elevated maternal and fetal morbidity rates

Haematologica, 2023
Laure Joseph, Gonzalo De Luna, Emmanuelle Bernit, Pierre Cougoul, Aline Santin, Benoit Faucher, Anoosha Habibi, Alain Garou, Gylna Loko, Sarah Mattioni, Sandra Manceau, Jean Benoit Arlet, François Lionnet   +12 more
doaj   +1 more source

Posterior reversible encephalopathy syndrome secondary to asymptomatic poststreptococcal glomerulonephritis in a child with sickle cell anemia: a case report

Journal of Medical Case Reports, 2018
Background Posterior reversible encephalopathy syndrome is a neurotoxic condition that occurs as a result of the failure of posterior circulatory autoregulation in response to acute changes in blood pressure.
Ehab Hanafy, Duaa Alshareef, Suhaila Osman, Abdullah Al Jabri, Faisal Nazim, Gihan Mahmoud   +5 more
doaj   +1 more source

Controlled trial of transfusions for silent cerebral infarcts in sickle cell anemia.

New England Journal of Medicine, 2014
BACKGROUND Silent cerebral infarcts are the most common neurologic injury in children with sickle cell anemia and are associated with the recurrence of an infarct (stroke or silent cerebral infarct).
M. DeBaun, M. Gordon, R. C. McKinstry, M. Noetzel, D. A. White, S. A. Sarnaik, R. E., Meier, T. H. Howard, S. Majumdar, B. P. D. Inusa, P. Telfer, M. Kirby-Allen, T. McCavit, A., Kamdem, G. Airewele, G. Woods, B. Berman, J. Panepinto, B. R. Fuh, J. L. Kwiatkowski, A. A. King, J. Fixler, M. Rhodes, A. A. Thompson, M. Heiny, R. C. Redding-Lallinger, F. Kirkham, N. Dixon, C. E. Gonzalez, K. Kalinyak, C. T. Quinn, J. Strouse, J. Miller, H. Lehmann, M. A. Kraut, W. Ball, D. Hirtz, J. F. Casella   +39 more
semanticscholar   +1 more source

Association between hemolysis and albuminuria in adults with sickle cell anemia

Haematologica, 2012
Studies have questioned whether renal dysfunction in sickle cell disease is linked to hemolysis-associated vasculopathy. We have investigated renal function and markers of hemolysis in a cohort of 424 adult African-British patients with sickle cell ...
Thomas G. Day, Emma R. Drasar, Tony Fulford, Claire C. Sharpe, Swee Lay Thein   +4 more
doaj   +1 more source

Sickle cell disease status among school adolescents and their tribal community in South Gujarat [PDF]

, 2009
Objectives: to create awareness, to screen samples of school adolescents and then to reach their community through them by doing surveillance for sickle cell disease. Design: Field based cross-sectional study. Settings: St Xavier`s high school and Vanraj
Chudasama, Rajesh K, Godara, Naresh R, Srivastava, Ratan K, Vasava, Bipin   +3 more
core   +1 more source

Silent Infarcts with Sickle Cell Anemia

Pediatric Neurology Briefs, 2002
The effect of transfusion therapy on the risk for new silent infarct or stroke in children with sickle cell anemia and abnormal transcranial Doppler (TCD) ultrasonography was determined at the University of Miami, FL, and other centers in the STOP trial (
J Gordon Millichap
doaj   +1 more source

J Rare Dis Res Treat [PDF]

Sickle cell disease affects more than 100,000 individuals in the United States, among whom disease severity varies considerably. One factor that influences disease severity is the sickle cell disease genotype.

core  

Reaching Community Through School Going Children for Sickle Cell Disease in Zankhvav Village of Surat District, Western India [PDF]

, 2012
Objectives: The objective of the study was to explore a method to reach the community via school going adolescents for screening tribal people for Sickle Cell disease.
Bansal, R, Gharat, VV, Mallick, KH, Rupani, MP, Vasava, BC   +4 more
core   +1 more source

Intestine-specific Disruption of Hypoxia-inducible Factor (HIF)-2α Improves Anemia in Sickle Cell Disease*

Journal of Biological Chemistry, 2015
Background: Sickle cell disease is an inherited blood disorder resulting in severe anemia. Results: Limiting iron toxicity through disruption of intestinal HIF-2α improves the anemia.
Nupur K. Das, Liwei Xie, S. Ramakrishnan, A. Campbell, S. Rivella, Y. Shah   +5 more
semanticscholar   +1 more source

A Phase Ib open label, randomized, safety study of SANGUINATE™ in patients with sickle cell anemia

Revista Brasileira de Hematologia e Hemoterapia
Background: Treatment of sickle cell anemia is a challenging task and despite the well understood genetic and biochemical pathway of sickle hemoglobin, current therapy continues to be limited to the symptomatic treatment of pain, supplemental oxygen ...
Hemant Misra, James Bainbridge, John Berryman, Abraham Abuchowski, Kenneth Mauricio Galvez, Luis Fernando Uribe, Angel Luis Hernandez, Nestor Rodolfo Sosa   +7 more
doaj   +1 more source