Results 141 to 150 of about 216,468 (292)

Hair‐on‐end sign in severe sickle cell disease

British Journal of Haematology, EarlyView.
Raquel da Costa Neves, Joana Pais de Faria, Paula Kjöllerström   +2 more
wiley   +1 more source

Early exposure, enduring consequences: How do I manage Rh immunoglobulin prophylaxis after Rh‐mismatched transfusions in children?

Transfusion, EarlyView.
Abstract Background RhD mismatched transfusions in RhD negative women have the potential to impact future pregnancies through alloimmunization and development of hemolytic disease of the fetus and newborn (HDFN). As use of RhD positive emergency‐release blood products in pediatric trauma has increased, it has become clear that a significant ...
Kirea Lange, Alexander Bowers, Niruktha Raghavan, Hannah Borland, Leslie Greebon, Christine Leeper, Barbara Gaines, Donald Jenkins   +7 more
wiley   +1 more source

Addressing racial disparities in representation across blood, stem cell and organ and tissue donor pools

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Adequate representation of donors from diverse ancestral populations in blood, stem cell and organ transplantation is critical to ensuring equitable access to these lifesaving therapies. Because of population‐level differences in genetic markers, patients from racialized groups may have unique transfusion and ...
Bonnie Lu, Sylvia Okonofua, Farnaz Farahbakhsh, Rupal Hatkar, Lauren Sano, Margarita Conway, Marie‐Claire Kapesa, Manuel Escoto, Murdoch Leeies, Warren B. Fingrut   +9 more
wiley   +1 more source

Hypoxic‐hypocapnic red blood cells in PAGGSM additive solution before and after gamma irradiation show improved metabolism

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Hypoxic/hypocapnic (HH) treatment and storage conditions have been shown to reduce oxidative stress and improve red blood cell (RBC) quality. This study aimed to validate a good manufacturing practice HH RBC product for obtaining the licence for routine use in patients, by comparison with normoxic RBCs both without ...
Soroth Chey, Jacqueline Maier, Samuel Sowemimo‐Coker, Reinhard Henschler   +3 more
wiley   +1 more source

Soluble transferrin receptor in sickle cell diseases: correlation with spleen function

São Paulo Medical Journal
OBJECTIVE: To correlate spleen function with soluble transferrin receptor (sTfR) levels and red cell ferritin (RCF) values in patients with sickle cell diseases. DESIGN: Prospective study.
Helena Zerlotti Wolf Grotto, Elza Miyuki Kimura, Márcia Victor Carneiro   +2 more
doaj   +1 more source

Predictors of impending acute chest syndrome in patients with sickle cell anaemia. [PDF]

, 2020
Acute chest syndrome (ACS) is a major complication of sickle cell anaemia (SCA) and a leading cause for hospital admissions and death. We aimed to study the spectrum of clinical and laboratory features of ACS and to assess the predisposing factors and ...
Al-Busaidi, Ikhlas, Al-Salami, Bushra, Alkindi, Salam, Ballas, Samir K., Pathare, Anil, Raniga, Samir   +5 more
core   +1 more source

International multicentre evaluation of a new anti‐idiotypic anti‐daratumumab for resolving pre‐transfusion interferences

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Daratumumab, a therapeutic human anti‐CD38 monoclonal antibody, improves multiple myeloma outcomes but interferes with pre‐transfusion testing by binding CD38 on reagent red blood cells (RBCs), potentially masking clinically significant alloantibodies.
Arnaud Reggiani, Sofia Lejon Crottet, Sophie Waldvogel, Charlotte Engström, Serelina Coluzzi, Antonella Matteocci, Janis R. Hamilton, Levent Tufan Kumas, Karen M. K. de Vooght, Jill R. Storry, Jennylyn Flores, Núria Nogués, Carlos Cotorruelo, Molly Rutherford, Eveline B. Nilsen, Monika Pelc‐Kłopotowska, Jolanta Korzeniowska, Alessandra Baffa, Inna Sareneva, Nor Hafizah Ahmad, Katarzyna Szczudlo, Athif Rahman, Laser Sanal, Lise Jørgensen, Karolina Majewska Rochowiak, Monika Salwierz, Elisaveta Grancharova, Bojana Zivkovic, Jessica Alvarez, Mareike Riedl, Achim Knappik   +30 more
wiley   +1 more source

Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia. Investigators of the Multicenter Study of Hydroxyurea in Sickle Cell Anemia.

New England Journal of Medicine, 1995
S. Charache, M. Terrin, R. Moore, G. Dover, F. Barton, Susan V. Eckert, R. Mcmahon, D. Bonds   +7 more
semanticscholar   +1 more source

Metabolic stimulation improves bioenergetics and haematologic indices of circulating erythrocytes from sickle cell mice

The Journal of Physiology, EarlyView.
Abstract figure legend Metabolic stimulation improves bioenergetics, redox state, hydration and hematologic indices of circulating erythrocytes from sickle cell mice. Retained mitochondria in circulating RBCs from sickle mice are a source of RBC ATP as mitochondria function (ETC, electron transport chain) inhibitors [rotenone, a mitochondrial complex I
Luis E. F. Almeida, Meghann L. Smith, Sayuri Kamimura, Sebastian Vogel, Zenaide M. N. Quezado   +4 more
wiley   +1 more source

Implementation of an Integrated Pharmacology Curriculum in a Flipped, Small‐Group, Case‐Based, Pre‐Clerkship Medical Curriculum Improved Student Performance

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Rush Medical College implemented a new, integrated pre‐clerkship curriculum. Pharmacology was integrated with other basic sciences into a flipped, small‐group, case‐based structure. This report describes the main features of the pharmacology curriculum for pharmacology directors to have a template.
Brinda Desai Bradaric, Eric Van Rite, Lalita Prasad‐Reddy, Michael Bradaric   +3 more
wiley   +1 more source