Results 1 to 10 of about 105,245 (307)

Predictors of Acute Chest Syndrome Following Vaso-Occlusive Crisis in Pediatric Sickle Cell Disease [PDF]

Diagnostics
Background/Objectives: Acute chest syndrome (ACS) is a frequent and potentially life-threatening complication of sickle cell disease (SCD) that often develops during hospitalization for vaso-occlusive crisis (VOC).
Narcisse Elenga, Noelis Thomas Boizan, Emmanuel Irakoze, Mody Diop, Gabriel Bafunyembaka   +4 more
doaj   +2 more sources

Associated Factors of Cholelithiasis among Younger Children with Sickle Cell Disease at the National Reference Center for Sickle Cell Disease in Brazzaville, Congo

Anemia, 2023
Introduction. Chronic hemolysis predisposes sickle cell patients to the development of gallstones. Their frequency increases with age, but they may appear early in young children.
Firmine Olivia Galiba Atipo Tsiba, Clément Pacha Mikia, Jennifer Armandine Elira Samba, Jade Vanessa Nziengui Mboumba, Félix Malanda, Clausina Mikolele Ahoui, Alexis Elira Dokekias   +6 more
doaj   +1 more source

The efficacy of maternal health education and maternal screening on knowledge and the uptake of infant screening for sickle cell disease in Dar-Es-Salaam, Tanzania; a quasi experimental study

BMC Public Health, 2023
Background Globally, Sickle cell disease (SCD) is one of the most common genetic disease with high childhood mortality. Early identification of babies with SCD through newborn screening (NBS) and linking them to care are among the recommended ...
Hilda J. Tutuba, Agnes Jonathan, William Lloyd, Upendo Masamu, Emanuela Marco, Julie Makani, Paschal Ruggajo, Benson R. Kidenya, Irene K. Minja, Emmanuel Balandya   +9 more
doaj   +1 more source

The Effect of COVID-19 on Hemoglobinopathy Patients’ Daily Lives While Quarantined: Four Greek Hospitals’ Experiences

Thalassemia Reports, 2022
During a pandemic, people are fearful of becoming infected with the virus, which causes anxiety, loss of purpose, and depression. This study aimed to evaluate the social and psychological impact, as well as the impact on homecare, of patients with ...
Sophia Delicou, Aikaterini Xydaki, Konstantinos Manganas, Emmanouil Koullias, Loukia Evliati, Chryssoula Kalkana, Michael D. Diamantidis, Achilles Manafas, Marianna Katsatou, Leonidas Roumpatis, Theodoros Aforozis   +10 more
doaj   +1 more source

Sickle cell disease patients with COVID‐19 in Guadeloupe: Surprisingly favorable outcomes

eJHaem, 2022
We investigate risk factors for hospitalization and difference between sickle cell syndromes in a cohort of COVID‐19 sickle cell disease (SCD) adult patients managed in the Reference Center of Guadeloupe.
Emmanuelle Bernit, Marc Romana, Scylia Alexis‐Fardini, Vanessa Tarer, Pierre‐Marie Roger, Lydia Doumdo, Eléonore Petras, Corine Charneau, Benoit Tressières, Marie Dominique Hardy Dessources, Maryse Etienne‐Julan   +10 more
doaj   +1 more source

Patterns and patient factors associated with loss to follow-up in the Muhimbili sickle cell cohort, Tanzania

BMC Health Services Research, 2020
Background Monitoring patient’s clinical attendance is a crucial means of improving retention in care and treatment programmes. Sickle cell patients’ outcomes are improved by participation in comprehensive care programmes, but these benefits cannot be ...
Upendo Masamu, Raphael Z. Sangeda, Daniel Kandonga, Jesca Ondengo, Flora Ndobho, Bruno Mmbando, Siana Nkya, Khadija Msami, Julie Makani   +8 more
doaj   +1 more source

HIV-1 Tat phosphorylation on Ser-16 residue modulates HIV-1 transcription

Retrovirology, 2018
Background HIV-1 transcription activator protein Tat is phosphorylated in vitro by CDK2 and DNA-PK on Ser-16 residue and by PKR on Tat Ser-46 residue. Here we analyzed Tat phosphorylation in cultured cells and its functionality. Results Mass spectrometry
Andrey Ivanov, Xionghao Lin, Tatiana Ammosova, Andrey V. Ilatovskiy, Namita Kumari, Hatajai Lassiter, Nowah Afangbedji, Xiaomei Niu, Michael G. Petukhov, Sergei Nekhai   +9 more
doaj   +1 more source

Concomitant Presence of Hb Agrinio and - -Med Deletion in a Greek Male Patient with Hemoglobinopathy H: More Severe Phenotype and Literature Review

Hematology Reports, 2023
Hemoglobin (Hb) Agrinio is a rare non-deletional a-globin mutation observed almost exclusively in Greek, Spanish or other Mediterranean families. The clinical manifestations of a carrier of a single Hb Agrinio mutation (single heterozygosity) depend on ...
Michael D. Diamantidis, Stefania Pitsava, Omar Zayed, Ioanna Argyrakouli, Konstantinos Karapiperis, Christos Chatzoulis, Evangelos Alexiou, Achilles Manafas, Evangelos Tsangalas, Konstantinos Karakoussis   +9 more
doaj   +1 more source

Identification of the Rare, Four Repeat Allele of IL-4 Intron-3 VNTR Polymorphism in Indian Populations [PDF]

Iranian Journal of Immunology, 2016
Background: Cytokines are cell signaling molecules which upon release by cells facilitate the recruitment of immune-modulatory cells towards the sites of inflammation. Genetic variations in cytokine genes are shown to regulate their production and affect
Henu Kumar Verma, Aditya Nath Jha, Prafulla Kumar khodiar, Pradeep Kumar Patra, Lakkakula Venkata Kameswara Subrahmanya Bhaskar   +4 more
doaj  

Improving Screening Programmes for Sickle Cell Disorders and Other Haemoglobinopathies in Europe: The Role of Patient Organisations

International Journal of Neonatal Screening, 2019
This discussion paper has been written to show the unique contribution and added value that Patient Organisations can give to the development and improvement of newborn screening programmes for sickle cell disorder (SCD) and other haemoglobinopathies in ...
John James, Elizabeth Dormandy
doaj   +1 more source