Results 11 to 20 of about 4,991,463 (296)
Knowledge and Attitudes towards Sickle Cell Disease Screening: A Study of Members of the UK Sickle Cell Society [PDF]
Over the past fifty years there has been an increase in the number of people in the UK who have a Sickle Cell Disorder (SCD) or are carriers. This increase has led to an expansion in research in this area; however one particular area that has not been ...
Millan, Jenny +2 more
core +9 more sources
Peripartum Anesthetic Management of a Patient With Sickle Cell Disease and Preeclampsia. [PDF]
ABSTRACT Peripartum care for patients with sickle cell disease and preeclampsia requires coordinated multidisciplinary management. Key strategies include multimodal analgesia, individualized transfusion protocols, and vigilant maternalāfetal monitoring.
Dow M, Srinivasan A, Ayad S.
europepmc +2 more sources
Nutritional status, hospitalization and mortality among patients with sickle cell anemia in Tanzania. [PDF]
BACKGROUND: Reduced growth is common in children with sickle cell anemia, but few data exist on associations with long-term clinical course. Our objective was to determine the prevalence of malnutrition at enrollment into a hospital-based cohort and ...
Soka, Deogratius +27 more
core +1 more source
Evaluating Reproductive Health Recommendations in CPGs for Sickle Cell Disease: An Umbrella Review. [PDF]
ABSTRACT Background Individuals with sickle cell disease or trait (SCD/T) face significant reproductive health risks, highlighting the need to assess the best available evidence on their reproductive health needs. Objectives To assess the quality of SCD/T clinical practice guidelines and evaluate the key characteristics and quality of their ...
Roberts LR +4 more
europepmc +2 more sources
Bacteraemia in Kenyan children with sickle-cell anaemia: a retrospective cohort and case-control study. [PDF]
BACKGROUND: In sub-Saharan Africa, more than 90% of children with sickle-cell anaemia die before the diagnosis can be made. The causes of death are poorly documented, but bacterial sepsis is probably important.
Uyoga, Sophie +44 more
core +1 more source
Hemoglobin (Hb) Agrinio is a rare non-deletional a-globin mutation observed almost exclusively in Greek, Spanish or other Mediterranean families. The clinical manifestations of a carrier of a single Hb Agrinio mutation (single heterozygosity) depend on ...
Michael D. Diamantidis +9 more
doaj +1 more source
Fat embolization syndrome (FES) is often seen as a complication of fractures and has been known to cause respiratory failure, rashes of the skin, thrombocytopenia, and neurological damage.
Ram Prakash Thirugnanasambandam +4 more
doaj +1 more source
This discussion paper has been written to show the unique contribution and added value that Patient Organisations can give to the development and improvement of newborn screening programmes for sickle cell disorder (SCD) and other haemoglobinopathies in ...
John James, Elizabeth Dormandy
doaj +1 more source
Hematological and biochemical reference values in sickle cell disease (SCD) are crucial for patient management and the evaluation of interventions. This study was conducted at Muhimbili National Hospital (MNH) in Dar es Salaam, Tanzania, to establish ...
Anna Daniel Fome +9 more
doaj +1 more source
Protein Phosphatase-1 Regulates Expression of Neuregulin-1
Protein phosphatase 1 (PP1), a cellular serine/threonine phosphatase, is targeted to cellular promoters by its major regulatory subunits, PP1 nuclear targeting subunit, nuclear inhibitor of PP1 (NIPP1) and RepoMan.
Tatiana Ammosova +7 more
doaj +1 more source

