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International journal of engineering development and research
Westudied the role of the sodium-potassium pump in erythrocytes of 12 patients with sickle cell anemia (SS). Ouabain-binding sites per cell and pump-mediated Rb/K uptake were significantly higher in SS patients than in white or black controls ...
Raksha.N Raksha.N +2 more
semanticscholar +1 more source
Westudied the role of the sodium-potassium pump in erythrocytes of 12 patients with sickle cell anemia (SS). Ouabain-binding sites per cell and pump-mediated Rb/K uptake were significantly higher in SS patients than in white or black controls ...
Raksha.N Raksha.N +2 more
semanticscholar +1 more source
Annals of Internal Medicine, 1978
Excerpt To the editor: The "natural history" of sickle cell anemia in Saudi Arabs (Ann Intern Med88:1-6, 1978) is certainly different from the disease as we see it in the United States but not as d...
openaire +2 more sources
Excerpt To the editor: The "natural history" of sickle cell anemia in Saudi Arabs (Ann Intern Med88:1-6, 1978) is certainly different from the disease as we see it in the United States but not as d...
openaire +2 more sources
Genetics of Sickle Cell Anemia Disorders in Baghdad City, Iraq
Indian Journal of Public Health Research & Development, 2019The results show that the number of patients in Al-Iskan District surpassed that in Al-Harthiyya. Moreover, in studying the spread of Malaria disease and its relation to Sickle cell anemia, it has been noticed that patients infected with Malaria were ...
Eqbal Dohan Chillab +2 more
semanticscholar +1 more source
2010
Sickle cell anemia (SCA or SS homozygous sickle cell disease) is an inherited blood disorder caused by single nucleotide substitution in the β-globin gene that renders their hemoglobin (HbS) much less soluble than normal hemoglobin (HbA) when deoxygenated. The polymerization of HbS upon deoxygenation is the basic pathophysiologic event leading
Connes Philippe +3 more
openaire +1 more source
Sickle cell anemia (SCA or SS homozygous sickle cell disease) is an inherited blood disorder caused by single nucleotide substitution in the β-globin gene that renders their hemoglobin (HbS) much less soluble than normal hemoglobin (HbA) when deoxygenated. The polymerization of HbS upon deoxygenation is the basic pathophysiologic event leading
Connes Philippe +3 more
openaire +1 more source
Natural history of sickle cell anemia in Saudi Arabs. A study of 270 subjects.
Annals of Internal Medicine, 2020R. P. Perrine +4 more
semanticscholar +1 more source
2014
Sickle cell anemia is one of the first diseases understood at the molecular level. Valine substituted for glutamic acid in the beta globin subunit leads to decreased solubility in the de-oxygenated state. It may partially protect infants from cerebral falciparum malaria in the heterozygous state (sickle trait), and geographic distribution of the ...
openaire +1 more source
Sickle cell anemia is one of the first diseases understood at the molecular level. Valine substituted for glutamic acid in the beta globin subunit leads to decreased solubility in the de-oxygenated state. It may partially protect infants from cerebral falciparum malaria in the heterozygous state (sickle trait), and geographic distribution of the ...
openaire +1 more source