Results 81 to 90 of about 216,468 (292)

G‐CSF for Mobilizing CD34+ Cells in Individuals With SCD: A Word of Caution

American Journal of Hematology, EarlyView.
Akshay Sharma, Allistair Abraham, Monica Bhatia, María Cancio, Sonali Chaudhury, Selim Corbacioglu, Gregory M. T. Guilcher, Ashish O. Gupta, Rabi Hanna, Matthew M. Heeney, Tami John, Lakshmanan Krishnamurti, James L. LaBelle, Hemalatha G. Rangarajan, Shalini Shenoy, Elizabeth Stenger, Crawford Strunk, Courtney D. Fitzhugh   +17 more
wiley   +1 more source

Immune Imbalance in Sickle Cell Anemia: Flow Cytometric Insights Into Regulatory T Cells and Neutrophil Dynamics

Journal of Clinical Laboratory Analysis, EarlyView.
Flow cytometric analysis in sickle cell anemia reveals preserved Treg frequency despite decreased CD25 expression and increased neutrophil activity, highlighting a complex immune imbalance. The proportions of both neutrophil and lymphocyte cells have been shown to be a reliable predictor of CD3+ T cell levels, thus emphasizing the importance of innate ...
Rukiye Ölçüoğlu, Funda Tanrıkulu, Sevtap Kılınç, Eda Çakmak, Süheyl Asma, Can Boğa, Hakan Özdoğu, İlknur Pamuk   +7 more
wiley   +1 more source

Positive depression screening and associated factors among children with sickle cell anemia attending a tertiary hospital in Mwanza, Tanzania: A Cross-sectional study

Journal of Affective Disorders Reports
Background: Depression is an increasingly important public health concern among children, particularly those living with chronic illnesses, including sickle cell anemia.
Eunice H. Barnabas, Matiko Mwita, Rogatus M. Kabyemera, Emmanuela E. Ambrose   +3 more
doaj   +1 more source

Prenatal Exome Sequencing Identifies Dual Maternal‐Fetal Diagnosis of HbF Mission Bay, a Novel HBG2 Variant Associated With Methemoglobinemia, Hypoxia and Hemolytic Anemia

Prenatal Diagnosis, EarlyView.
ABSTRACT Prenatal exome sequencing (ES) can establish rare genetic diagnoses in a fetus but may also lead to occult genetic diagnosis in a biological parent. We present a case of dual fetal and maternal diagnosis by prenatal ES, in a fetus with unexplained anemia and in a pregnant patient with sickle cell disease (SCD) and recurrent unexplained hypoxia.
Matthew A. Shear, Billie Lianoglou, Ugur Hodoglugil, W. Patrick Devine, Ashutosh Lal, Juan Gonzalez, Teresa N. Sparks   +6 more
wiley   +1 more source

Hipertensão arterial pulmonar associada à anemia falciforme Sickle cell anemia-associated pulmonary arterial hypertension

Jornal Brasileiro de Pneumologia, 2007
A hipertensão pulmonar é uma complicação comum em pacientes com anemia falciforme. A despeito das elevações leves das pressões pulmonares desses pacientes, a morbimortalidade é alta e, em pacientes adultos com anemia falciforme, a hipertensão pulmonar é ...
Roberto Ferreira Pinto Machado
doaj   +1 more source

Cannabinoid receptor-specific mechanisms to alleviate pain in sickle cell anemia via inhibition of mast cell activation and neurogenic inflammation

Haematologica, 2016
Sickle cell anemia is a manifestation of a single point mutation in hemoglobin, but inflammation and pain are the insignia of this disease which can start in infancy and continue throughout life.
Lucile Vincent, Derek Vang, J. Nguyen, B. Benson, Jianxun Lei, K. Gupta   +5 more
semanticscholar   +1 more source

Compound Heterozygosity for Hemoglobin S and Hemoglobin LuLu Island

American Journal of Hematology, EarlyView.
Dana Lewis, Thomas Lofaro, Laura Fraser, Sheana Wijemanne, Barbara J. Bain   +4 more
wiley   +1 more source

The Expanding Role of Gene Sequencing in Shaping Fetal Therapies: Clinical and Ethical Considerations

Prenatal Diagnosis, EarlyView.
ABSTRACT In utero interventions are transformative in addressing genetic and anatomic conditions during fetal development. Next generation sequencing enables early genetic testing, playing a pivotal role in prenatal decision‐making by supporting risk stratification, precise and timely diagnosis, which directly informs eligibility for fetal surgical and
Matthew A. Shear, Beltran Borges, Billie R. Lianoglou, Tony Lum, Emma Canepa, Jennifer L. Cohen, Julia E. H. Brown, Akos Herzeg   +7 more
wiley   +1 more source

Barnes Hospital Bulletin [PDF]

, 1979
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1167/thumbnail ...

core   +1 more source

Reversibility of Red blood Cell deformation

, 2011
The ability of cells to undergo reversible shape changes is often crucial to their survival. For Red Blood Cells (RBCs), irreversible alteration of the cell shape and flexibility often causes anemia.
C. T. Noguchi, G. Lim, H. Goldstein, L. D. Landau, Maria Zeitz, P. Sens   +5 more
core   +1 more source