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Sickle cell disease complicating pregnancy: A retrospective study
Introduction: Sickle cell disease is an uncommon cause of anemia and jaundice during pregnancy. Sickle cell crisis may lead to several maternal and fetal complications. Aims: To study maternal and fetal complications in pregnant patients with sickle cell
B Kavitha, Basanta H Hota
doaj +1 more source
Gene therapy is revolutionizing treatment paradigms for haemoglobinopathies, establishing a translational framework for disorders that impact red blood cell development. In their paper, Joshi et al. describe the preclinical and early clinical landscape of gene therapies for non‐haemoglobinopathy erythroid disorders and highlight common thematic ...
Gaurav Joshi +3 more
wiley +1 more source
Sickle Cell Data Collection Program Brief : Hospital Encounters Among Adults Living With Sickle Cell Disease in Georgia 2012-2016 [PDF]
The Georgia Sickle Cell Data Collection Program (SCDC) identified 5,405 adults living with sickle cell disease in Georgia from 2012 through 2016. Adults with sickle cell disease live in almost every county throughout Georgia.Nearly nine in 10 (88%) of ...
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Duodenal perforation: an unusual complication of sickle cell anemia
Duodenal perforation in childhood is a rare condition with a high mortality rate if not treated surgically. Primary gastroduodenal perforation is frequently associated with peptic ulcer and exhibits a positive family history.
Can Acıpayam +5 more
doaj +1 more source
Predict less, prevent more: A familiar mantra for sickle cell anaemia?
Commentary on: Sommet J, Boizeau P, Haouari Z, et al. Identification of predictive factors for reversal of cerebral vasculopathy in an original longitudinal cohort study in newborns with sickle cell anaemia. Br J Haematol. 2026 (Online ahead of print). doi: 10.1111/bjh.70726.
Charles T. Quinn
wiley +1 more source
Sickle Cell Disease (SCD) in California, 2016 [PDF]
We found 4,689 people with SCD were living in California in 2016.CS 310397-C2016-snapshot-sickle-cell-ca-508.pdf?deliveryName=USCDC_1391 ...
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Background: Individuals with sickle cell anemia may suffer symptomatic or silent cerebral infarcts leading to neurocognitive complications. This study investigated the cognitive and intellectual performance of children and adolescents with sickle cell ...
Samantha Nunes +4 more
doaj +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.
Pedro Junqueira Fleury Silva +12 more
wiley +1 more source
Summary Cerebral macrovasculopathy (CV) is a major complication in children with sickle cell anaemia (SCA) and usually requires a long‐term transfusion programme (TP) to prevent stroke. This study aimed to identify factors predicting reversal of CV on TP in a single‐centre newborn cohort. Among 375 patients, 50 presented CV and received TP.
Julie Sommet +16 more
wiley +1 more source
Sildenafil Citrate-Restored eNOS and PDE5 Regulation in Sickle Cell Mouse Penis Prevents Priapism Via Control of Oxidative/Nitrosative Stress [PDF]
Sildenafil citrate revolutionized the practice of sexual medicine upon its federal regulatory agency approval approximately 15 years ago as the prototypical phosphodiesterase type 5 inhibitor indicated for the treatment of male erectile dysfunction.
Berkowitz, Dan E +29 more
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