Redefining the role of the transfusion medicine physician in the era of advanced cellular therapies
Transfusion, EarlyView.
Eric A. Gehrie, Kevin J. Land
wiley +1 more source
This study presents a deep learning framework for the automated authentication of 15 medicinal Apiaceae species using digital images of their mericarps. The pipeline integrates an augmentation module—incorporating rescaling, rotation, and flipping—to improve model generalization, followed by feature extraction using pre‐trained DenseNet121 as the core ...
Elyas Aryakia, Ersam Aryakia
wiley +1 more source
ABSTRACT Background and Aims Between 200,000 and 300,000 children with sickle cell disease (SCD) are born in Africa every year, with 75%–80% of these children living in sub‐Saharan Africa. In newborns with SCD, significant iron accumulations may develop because of their increased risk of requiring multiple blood transfusions. This study aimed to assess
John Agyemang Sah +10 more
wiley +1 more source
Fatal sickling-associated microvascular occlusive crisis in a young with sickle cell trait
Sickle cell trait (SCT), a heterozygous state characterized by hemoglobin AS, occurs commonly in sub-Saharan Africa, South America, Central America, India, and the Mediterranean countries.
Deepti Mutreja +2 more
doaj
Appraisal of patient-reported outcome measures in analogous diseases and recommendations for use in phase II and III clinical trials of pyruvate kinase deficiency [PDF]
Purpose: Pyruvate kinase deficiency (PKD) is a rare disease and understanding of its epidemiology and associated burden remains limited. With no current curative therapy, clinical manifestations can be life threatening, clinically managed by maintaining ...
Ionova, Tatyana +3 more
core +2 more sources
Online decision aids for contraceptive choices in women with chronic conditions: A systematic review
Abstract Background Women with chronic conditions face increased risks of unintended pregnancy and adverse maternal and perinatal outcomes. Tailored, online contraceptive decision aids might improve informed decision‐making and support reproductive health by promoting patient‐centered care in this population.
Begashaw Melaku Gebresillassie +2 more
wiley +1 more source
Unusual presentation of ocular trauma in sickle cell trait
Sickle cell trait is usually considered as a benign condition. However under certain adverse circumstances, it can give rise to vaso-occlusive features as in sickle cell disease.
Nidhi Pandey
doaj +1 more source
Medical haematology: Repositioning haematology at the centre of medicine
The complementary domains of Medical Haematology and Haemato‐Oncology share a biological framework. The left panel depicts red cells, platelets, coagulation, thrombosis and innate immunity, while the right panel shows lymphoid and myeloid malignancies.
Cheng Hock Toh, Imelda Bates, Sue Pavord
wiley +1 more source
Novel use Of Hydroxyurea in an African Region with Malaria (NOHARM): a trial for children with sickle cell anemia [PDF]
Hydroxyurea treatment is recommended for children with sickle cell anemia (SCA) living in high-resource malaria-free regions, but its safety and efficacy in malaria-endemic sub-Saharan Africa, where the greatest sickle-cell burden exists, remain unknown.
Hodges, James S. +8 more
core +2 more sources
Stroke burden and functional impacts in adults with sickle cell disease
Stroke was identified in 4.6% of 454 adults with sickle cell disease. Stroke occurred not only across HbSS/Sβ0 phenotypes but also HbSC/Sβ+ as well, challenging traditional assumptions. Stroke was associated with long‐term functional impairment, including cognitive deficits and higher disability scores.
Jonathan St‐Onge +12 more
wiley +1 more source

