Results 61 to 70 of about 28,210 (227)
Whole Blood Transcriptomic Analysis of Sickle Cell Trait
European Journal of Haematology, EarlyView.ABSTRACT Sickle cell trait (SCT) is the heterozygous carrier state for the HBB missense variant which causes sickle cell disease (SCD). SCT has been associated with increased risk of venous thromboembolism and chronic kidney disease as well as alterations in clinical laboratory parameters. To investigate differential gene expression in SCT, we used RNA
Mari Johnson +12 more
wiley +1 more source
The ethnic distribution of sickle cell disease in Sudan
The Pan African Medical Journal, 2014 Sickle cell disease (SCD) is one of the most common inherited disorders of haemoglobin in Africa and it is expected that sickle cell trait varies in frequency in different areas in Sudan.
Majdi Mohammed Sabahelzain, Hanan Hamamy
doaj +1 more source
Journal of Integrated Health Sciences, 2023 A structural flaw in the globin gene causes hemoglobinopathies, while a flaw in the globin chain’s synthesis causes thalassemia. One of the most prevalent hemoglobinopathies worldwide is sickle cell disease.
Divyesh Patel +4 more
doaj +1 more source
The epidemiology of chronic kidney disease (CKD) in rural East Africa: A population-based study. [PDF]
, 2020 BackgroundChronic kidney disease (CKD) may be common among individuals living in sub-Saharan Africa due to the confluence of CKD risk factors and genetic predisposition.MethodsWe ascertained the prevalence of CKD and its risk factors among a sample of 3 ...
Atukunda, Mucunguzi +14 more
core +2 more sources
Haemophilia, EarlyView.ABSTRACT Introduction The National Bleeding Disorder Foundation (NBDF) Medical and Scientific Advisory Council (MASAC) was formed in 1954 and issues recommendations and advisories pertinent to the bleeding disorders community. MASAC is comprised of > 25 rotating members from different medical disciplines and lived experience experts.
Glaivy Batsuli +15 more
wiley +1 more source
Oral Diseases, EarlyView.ABSTRACT Objective Patients with burning mouth syndrome (BMS) suffer from oral pain in the absence of oral lesions. Although less frequently, they may also experience extraoral symptoms that are not readily apparent to clinicians. This study aimed to systematically assess the prevalence of associated extraoral symptoms and comorbid disorders in BMS ...
João Paulo Gonçalves de Paiva +6 more
wiley +1 more source
PREVALENCE OF SICKLE CELL TRAIT IN THE SOUTHERN SUBURBS OF BEIRUT, LEBANON
Mediterranean Journal of Hematology and Infectious Diseases, 2016 Objectives: The objective of this study was to assess the prevalence, gender differences, and time trends of sickle cell trait in Beirut, Lebanon. Another objective was to describe a new screening technique for sickle cell trait carriers.
Abdel Badih El Ariss +3 more
doaj +1 more source
Revealing the molecular signatures of host-pathogen interactions. [PDF]
, 2011 Advances in sequencing technology and genome-wide association studies are now revealing the complex interactions between hosts and pathogen through genomic variation signatures, which arise from evolutionary co ...
C Herdtweck +53 more
core +13 more sources
Haematologica, 2019 Babesia divergens is an intra-erythrocytic parasite that causes malaria-like symptoms in infected people. As the erythrocyte provides the parasite with the infra-structure to grow and multiply, any perturbation to the cell should impact parasite ...
Jeny R. Cursino-Santos +5 more
doaj +1 more source
Vox Sanguinis, EarlyView.Abstract Background and Objectives Adequate representation of donors from diverse ancestral populations in blood, stem cell and organ transplantation is critical to ensuring equitable access to these lifesaving therapies. Because of population‐level differences in genetic markers, patients from racialized groups may have unique transfusion and ...
Bonnie Lu +9 more
wiley +1 more source