Results 211 to 220 of about 1,994,819 (333)

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

Advanced Science, EarlyView.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge, Jiamao Lin, Changsheng Yang, Chuanwang Miao, Fengxiang Li, Shuqiang Zhao, Lei Zou, Xuedong Teng, Lina Liu, Tingguang Li, Yan Sun, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Minxuan Xu, Minghui Chang, Jun Tan, Yanrong Ren, Bochu Wang   +21 more
wiley   +1 more source

Inpatient multimodal occupational rehabilitation reduces sickness absence among individuals with musculoskeletal and common mental health disorders: a randomized clinical trial

, 2020
Sigmund Gismervik, Lene Aasdahl, Ottar Vasseljen, Egil A. Fors, Marit By Rise, Roar Johnsen, Karen Walseth Hara, Henrik Børsting Jacobsen, Kristine Pape, Nils Fleten, Chris Jensen, Marius Steiro Fimland   +11 more
openalex   +2 more sources

Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen

Advanced Science, EarlyView.
Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang, Qing Wu, Hao‐Long Zeng, Yin Shen, Hong‐Han Zhang, Jun Gong, Qi Zhang, Jia‐Zhao Xie, Da‐Wei Ye, Zi‐Yong Sun, Zhong‐Chun Liu, Li‐Ming Cheng, Di Li   +12 more
wiley   +1 more source

Occupational class differences in long sickness absence: a register-based study of 2.1 million Finnish women and men in 1996–2013 [PDF]

, 2017
Johanna Pekkala, Jenni Blomgren, Olli Pietiläinen, Eero Lahelma, Ossi Rahkonen   +4 more
openalex   +1 more source

Alcohol Consumption and Sickness Absence: Evidence from Panel Data [PDF]

This paper examines the relationship between alcohol consumption and sickness absence. We use regional panel data from Finland over the period 1993-2005.
Böckerman, Petri, Johansson, Edvard, Uutela, Antti   +2 more
core   +1 more source

Taurocholic Acid Is Associated With Disturbed Functional Connectivity in the Hippocampus of Patients With Depression

Advanced Science, EarlyView.
This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai, Taipeng Sun, Mengzhen Feng, Gang Chen, Junchi Zhou, Hong Zhuang, Dan Wang, Ying Chen, Zhen Cheng, Zhi Xu, Xiao Zheng, Xueli Zhang, Yonggui Yuan   +12 more
wiley   +1 more source

Psychosocial working conditions for predicting long-term sickness absence in workers mental disorders [PDF]

, 2016
Giny Norder, JJL van der Klink, Ute Bültmann, CAM Roelen   +3 more
openalex   +1 more source

Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors

Advanced Science, EarlyView.
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen, Riya Gupta, Yosuke M. Morizawa, Yu Qin, Xingyu Du, Cynthia Pang, Osama Al‐Dalahmah, Maura B. Dupont, Guang Yang   +8 more
wiley   +1 more source

Sick of Robots-Heterogeneous Effects of Industrial Robots on Sickness Absence. [PDF]

Health Econ
Umblijs J, Østbakken KM.
europepmc   +1 more source

The effect of interdisciplinary treatment on sickness absence and disability pension among chronic pain patients on partial disability pension

Lea Constan, Paolo Frumento, Riccardo LoMartire   +2 more
openalex   +1 more source