Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways [PDF]
BMC Medicine, 2012 It is of considerable translational importance whether depression is a form or a consequence of sickness behavior. Sickness behavior is a behavioral complex induced by infections and immune trauma and mediated by pro-inflammatory cytokines.
Maes Michael +6 more
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Sickness Behavior in Honey Bees. [PDF]
Front Physiol, 2016 During an infection, animals suffer several changes in their normal physiology and behavior which may include lethargy, appetite loss, and reduction in grooming and general movements. This set of alterations is known as sickness behavior and although it has been extensively believed to be orchestrated primarily by the immune system, a relevant role for
Kazlauskas N +3 more
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Dexmedetomidine reduces lipopolysaccharide induced neuroinflammation, sickness behavior, and anhedonia. [PDF]
PLoS ONE, 2018 Peripheral innate immune response may induce sickness behavior through activating microglia, excessive cytokines production, and neuroinflammation. Dexmedetomidine (Dex) has anti-inflammatory effect.
Ching-Hua Yeh +6 more
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Propentofylline Prevents Sickness Behavior and Depressive-Like Behavior Induced by Lipopolysaccharide in Rats via Neuroinflammatory Pathway. [PDF]
PLoS ONE, 2017 Recent studies have demonstrated the intimate relationship between depression and immune disturbances. Aware of the efficacy limits of existing antidepressant drugs and the potential anti-inflammatory properties of propentofylline, we sought to evaluate ...
Márcia M T Moraes +8 more
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Sickness behavior and seasonal affective disorder: An immunological perspective of depression
Indian Journal of Psychological Medicine, 2018 We describe a case of 45-year-old female suffering from chronic hepatitis B and bronchial asthma who presented with symptoms of seasonal affective disorder and sickness behavior.
Pooja Patnaik Kuppili +2 more
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Immune Systems and Sickness Behavior [PDF]
, 2010 false ; 2016-03-16T16:38 ...
unknown ( host institution ) +1 more
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The Legacy of Sickness Behaviors [PDF]
Frontiers in Psychiatry, 2020 Systemic infections of all types lead to a syndrome known as sickness behaviors. Changes in the behavior of febrile humans and animals formed the original basis for this concept. Body temperature is behaviorally regulated in both endotherms and ectotherms.
Keith W. Kelley +4 more
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Signaling sickness: the role of recalled sickness behavior and psychosocial factors in shaping communication style. [PDF]
Evol Med Public Health, 2021 Background and objectives: Active infection results in several outward signs in humans, including visible symptoms, changes in behavior and possible alterations in skin color and gait.
Shattuck EC +4 more
europepmc +2 more sources
Zinc prevents sickness behavior induced by lipopolysaccharides after a stress challenge in rats. [PDF]
PLoS ONE, 2015 Sickness behavior is considered part of the specific beneficial adaptive behavioral and neuroimmune changes that occur in individuals in response to infectious/inflammatory processes.
Thiago B Kirsten +4 more
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How Does the Social Grouping of Animals in Nature Protect Against Sickness? A Perspective
Frontiers in Behavioral Neuroscience, 2021 Sickness behavior is broadly represented in vertebrates, usually in association with the fever response in response to acute infections. The reactions to sickness behavior in a group member or potential group member in humans is quite variable, depending
Lynette A. Hart, Benjamin L. Hart
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