Results 21 to 30 of about 23,218 (183)

Siderophores: More than Stealing Iron

mBio, 2016
Siderophores are small molecular iron chelators that are produced by microbes and whose most notable function is to sequester iron from the host and provide this essential metal nutrient to microbes.
Judith Behnsen, Manuela Raffatellu
doaj   +1 more source

Antibiotic resistance and siderophores production by clinical Escherichia coli strains

BioTechnologia, 2022
The phenomenon of antibiotic resistance has dramatically increased in the last few decades, especially in enterobacterial pathogens. Different strains of Escherichia coli have been reported to produce a variety of structurally different siderophores.
Mohamed Khazaal, Hoda H. El-Hendawy, Mona I. Mabrouk, Ahmed H. I. Faraag, Marwa R. Bakkar   +4 more
doaj   +1 more source

EFFECT OF SIDEROPHORES AGAINST E. COLI O157:H7

Italian Journal of Food Safety, 2012
In this study, the inhibiting activity of siderophores produced by Pseudomonas fluorescens against Escherichia coli O157:7 was assayed. Siderophores were extracted from P. fluorescens cultures and preliminarily tested by C.A.S. reagent and UV.
F. Giarratana, G. Ziino, D. Signorino, L. Giordano, A. Giuffrida   +4 more
doaj   +1 more source

Effect of salinity on the zinc(II) binding efficiency of siderophore functional groups and implications for salinity tolerance mechanisms in barley

Scientific Reports, 2021
Bacteria, fungi and grasses use siderophores to access micronutrients. Hence, the metal binding efficiency of siderophores is directly related to ecosystem productivity.
George H. R. Northover, Yiru Mao, Haris Ahmed, Salvador Blasco, Ramon Vilar, Enrique Garcia-España, Dominik J. Weiss   +6 more
doaj   +1 more source

Phenotypic Adaptation of Pseudomonas aeruginosa in the Presence of Siderophore-Antibiotic Conjugates during Epithelial Cell Infection

Microorganisms, 2020
Iron acquisition pathways have often been considered to be gateways for the uptake of antibiotics into bacteria. Bacteria excrete chelators, called siderophores, to access iron.
Quentin Perraud, Paola Cantero, Mathilde Munier, Françoise Hoegy, Nicolas Zill, Véronique Gasser, Gaëtan L. A. Mislin, Laurence Ehret-Sabatier, Isabelle J. Schalk   +8 more
doaj   +1 more source

Broad‐Spectrum, Cell Envelope‐Active Marinocyclin Antibiotics From a Coral‐Derived Bacterium Are Effective Against Colistin‐Resistant Bacteria

Angewandte Chemie, EarlyView.
Marinocyclins, polycationic macrocyclic depsipeptides, were discovered by genome mining from the marine coral‐derived bacterium Aquimarina megaterium. The compounds have broad‐spectrum activity against gram‐positive and gram‐negative ESKAPE bacteria.
Clara Chepkirui, Sandra Silva, Jan Straetener, Chandrashekhar Padhi, Tina Keller‐Costa, Tess Lamer, Laura Reinke, Heike Brötz‐Oesterhelt, Rodrigo Costa, Jörn Piel   +9 more
wiley   +2 more sources

Chemoenzymatic Radiosynthesis of a Gluconate Transporter‐Targeted In Vivo Bacterial Sensor From Clinical [18F]FDG

Angewandte Chemie, EarlyView.
An efficient radiosynthesis of fluorine‐18 labeled gluconic acid ([18F]FGA) was developed using two readily available materials, 2‐deoxy‐2‐[18F]fluoro‐D‐glucose ([18F]FDG) and glucose oxidase. [18F]FGA is highly specific for bacterial gluconate metabolism mediated by gluconate permease (GntP) and gluconate kinase (GntK), with rapid clearance, low off ...
Sang Hee Lee, Jung Min Kim, Joseph Blecha, Robert R. Flavell, Michael A. Ohliger, Joanne Engel, Youngho Seo, David M. Wilson   +7 more
wiley   +2 more sources

Sidérophores bactériens et fongiques : mécanisme de chélation et de transport du fer(III)

, 1999
International audienceNous présentons et discutons les paramètres thermodynamiques et cinétiques qui caractérisent le transport du fer(III) par deux sidérophores qui ont des structures chimiques différentes.
Grunenwald, Sylvie, Albrecht-Gary, Anne-Marie, Blanc, Sylvie   +2 more
core   +3 more sources

Hydroxamate production as a high affinity iron acquisition mechanism in Paracoccidioides spp. [PDF]

PLoS ONE, 2014
Iron is a micronutrient required by almost all living organisms, including fungi. Although this metal is abundant, its bioavailability is low either in aerobic environments or within mammalian hosts.
Mirelle Garcia Silva-Bailão, Elisa Flávia Luiz Cardoso Bailão, Beatrix Elisabeth Lechner, Gregory M Gauthier, Herbert Lindner, Alexandre Melo Bailão, Hubertus Haas, Célia Maria de Almeida Soares   +7 more
doaj   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source