Results 41 to 50 of about 23,218 (183)

Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy

Advanced Science, EarlyView.
Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song, Can Zhao, Qiaoling Wang, Hongjiao Zhang, Xiao Liu, Linqi Wang, Michael Bromley, Wen‐Bing Yin   +7 more
wiley   +1 more source

Beyond Probiotics: Postbiotics for Healthy Aquaculture

Advanced Science, EarlyView.
This critical review assesses limitations of probiotics and proposes postbiotics, preparations of inanimate microorganisms and their metabolites, as a more stable, controlled, and biosafe formulation. Postbiotics offer significant advantages during industrial aquafeed production and storage. However, their practical implementation is currently hindered
Michael Leonidas Chikindas, Delin Xu, Igor V. Popov, Kayque Ordonho Carneiro, Nilufar Arashovna Elova, Gullola Amirovna Bekmurodova, Dildora Amindjanovna Amirsaidova, Astghik Pepoyan, Shakhlo Mirjamalovna Miralimova, Oleg V. Mitrokhin, Liubov S. Sichel, John Tagg, Svetoslav Dimitrov Todorov   +12 more
wiley   +1 more source

Heavy Metal Contamination: Impacts From Plants to the Food Chain and Eco‐Friendly Amelioration Strategies

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Heavy metal pollution reduces soil health and threatens food safety by entering plants; however, the use of nanoparticles, biofertilizers, and organic fertilizers such as biochar offers a promising strategy for improvement and sustainable agriculture. ABSTRACT Heavy metal (HM) pollution, resulting from human activities such as mining and the excessive ...
Sina Siavash Moghaddam, Latifeh Pourakbar, Sevda Alizadeh, Zahra Alizadeh, Jelena Popović‐Djordjević   +4 more
wiley   +1 more source

Les sidérophores de Scedosporium apiospermum : identification, synthèse et applications

, 2009
Scedosporium apiospermum is an emerging pathogen colonizing the airways of patients with cystic fibrosis (CF) and causing severe infections in immunocompromised hosts. In order to improve our knowledge on the pathogenicity of this fungus, we investigated
Bertrand, Samuel
core   +3 more sources

Functional Plasticity of Microbial Siderophores in Iron- and Boron-Rich Niches

Applied Microbiology
Siderophores are high-affinity iron-chelating metabolites that underpin microbial survival in iron-limited environments and play central roles in metal homeostasis, ecological competition, and pathogenesis.
Valery M. Dembitsky, Alexander O. Terent’ev, Sergey V. Baranin   +2 more
doaj   +1 more source

Distribution and Cycling of Siderophores in the Eastern North and Tropical Pacific Oceans

Geophysical Research Letters
Most iron (Fe) dissolved in seawater is complexed to organic ligands of unknown composition. Here we investigate the distribution of siderophores, small organic compounds synthesized by microbes to bind environmental Fe and facilitate its transport into ...
Jingxuan Li, Lydia Babcock‐Adams, Matthew R. McIlvin, Daniel J. Repeta   +3 more
doaj   +1 more source

Siderophore production in Botryosphaeriaceae fungi associated with grapevine trunk diseases

The Microbe
Fungi from the Botryosphaeriaceae are recognized as causal agents of dieback diseases in a variety of economically important woody plants, including grapevine. Some species produce secondary metabolites that may function as virulent factors.
Edelweiss A. Rangel-Montoya, Andrea Páez-Gúzman, Laura J. Díaz-Rubio, Ivan Córdova-Guerrero, Rufina Hernandez-Martinez   +4 more
doaj   +1 more source

Catecholate siderophores protect bacteria from pyochelin toxicity. [PDF]

PLoS ONE, 2012
Bacteria produce small molecule iron chelators, known as siderophores, to facilitate the acquisition of iron from the environment. The synthesis of more than one siderophore and the production of multiple siderophore uptake systems by a single bacterial ...
Conrado Adler, Natalia S Corbalán, Mohammad R Seyedsayamdost, María Fernanda Pomares, Ricardo E de Cristóbal, Jon Clardy, Roberto Kolter, Paula A Vincent   +7 more
doaj   +1 more source

Variation in siderophore biosynthetic gene distribution and production across environmental and faecal populations of Escherichia coli. [PDF]

PLoS ONE, 2015
Iron is essential for Escherichia coli growth and survival in the host and the external environment, but its availability is generally low due to the poor solubility of its ferric form in aqueous environments and the presence of iron-withholding proteins
Laura J Searle, Guillaume Méric, Ida Porcelli, Samuel K Sheppard, Sacha Lucchini   +4 more
doaj   +1 more source

Perturber les voies de récupération du fer par les sidérophores de type catécholate pour limiter la virulence des Escherichia coli pathogènes aviaires. [PDF]

, 2013
Les Escherichia coli pathogènes extra-intestinaux sont capables de causer des infections urinaires, des septicémies et des méningites néo-natales chez l’homme, mais sont également responsables d’infections respiratoires causant de lourdes pertes dans les
Houle, Sébastien, Dozois, Charles M., Garénaux, Amélie, Chouinard-Pelletier, Catherine, Caza, Mélissa   +4 more
core   +2 more sources