Results 51 to 60 of about 23,218 (183)

Siderophore-Based Molecular Imaging of Fungal and Bacterial Infections—Current Status and Future Perspectives

Journal of Fungi, 2020
Invasive fungal infections such as aspergillosis are life-threatening diseases mainly affecting immuno-compromised patients. The diagnosis of fungal infections is difficult, lacking specificity and sensitivity.
Milos Petrik, Joachim Pfister, Matthias Misslinger, Clemens Decristoforo, Hubertus Haas   +4 more
doaj   +1 more source

Phenotypic and genotypic characterization of Pseudomonas aeruginosa siderophores

Zagazig Journal of Pharmaceutical Sciences, 2018
Pseudomonas aeruginosa is an opportunistic human pathogen that causes many infections such as urinary tract, respiratory tract, burn infections in addition to septicemia.
Ashraf Kadry , Marwa Ezz , Hisham A. Abbas   +2 more
doaj   +1 more source

Enhancing the Secretion Systems: Genetic Engineering of Super Bioagents for Effective Plant Disease Control

Biotechnology and Bioengineering, EarlyView.
Genetic engineering (GE) overcomes BCA limits, enabling robust, scalable crop protection. “Super Bioagents” (SBs) use optimized SSs to enhance bioactive molecule delivery. Optimizing SSs enhance precise, sustainable effector deployment for stable disease suppression. SBs use microbiome‐informed design for scalable, next‐gen sustainable crop protection.
Michael Dare Asemoloye
wiley   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

Rôles des sidérophores bactériens et de mammifères dans les interactions hôtes-pathogènes [PDF]

, 2015
Le fer est un nutriment essentiel à la vie de tout organisme vivant, des bactéries jusqu’à l’homme. En dépit de ce rôle clé dans le vivant, le fer à forte concentration est toxique. Dans notre organisme, pour contourner ce problème de toxicité, la grande
Schalk, Isabelle, Sophie Vaulont, Schalk, I. (Isabelle), Vaulont, Sophie, Vaulont, S. (Sophie), Isabelle Schalk   +5 more
core   +1 more source

Advances in Mycobacterium siderophore-based drug discovery

Acta Pharmaceutica Sinica B, 2011
Tuberculosis remains a public health threat of global proportions. Iron is a scarce resource indispensable to both host and pathogen during infection with Mycobacterium tuberculosis, the causative agent of tuberculosis.
Jun-li He, Jian-ping Xie
doaj   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

The role of FoxA, FiuA, and FpvB in iron acquisition via hydroxamate-type siderophores in Pseudomonas aeruginosa

Scientific Reports
Siderophores are specialized molecules produced by bacteria and fungi to scavenge iron, a crucial nutrient for growth and metabolism. Catecholate-type siderophores are mainly produced by bacteria, while hydroxamates are mostly from fungi.
Virginie Will, Chloé Frey, Vincent Normant, Lauriane Kuhn, Johana Chicher, Florian Volck, Isabelle J. Schalk   +6 more
doaj   +1 more source

Possible Mechanisms of Action of Two Pseudomonas fluorescens Isolates as Probiotics on Saprolegniosis Control in Rainbow Trout (Oncorhynchus mykiss Walbaum)

Animals, 2020
Probiotics have been proposed as one of the alternatives to the chemical treatments currently used in aquaculture. Recently, the possible usefulness of certain microorganisms, mainly bacteria, has been highlighted as a potential biocontrol for ...
Concepción González-Palacios, Juan-Miguel Fregeneda-Grandes, José-Miguel Aller-Gancedo   +2 more
doaj   +1 more source

Interpretation of Key Updates in the 36th Edition of Clinical and Laboratory Standards Institute M100 Standard

iLABMED, EarlyView.
ABSTRACT The Clinical and Laboratory Standards Institute M100 document serves as a cornerstone standard for clinical microbiology laboratories in China. Maintaining the scientific rigor of its predecessors, the 36th edition incorporates updated epidemiological cutoff values, pharmacokinetic/pharmacodynamic data, and clinical efficacy evidence to revise
Kanghong Xu, Qi Wang, Hui Wang
wiley   +1 more source