Results 1 to 10 of about 114,921 (219)

The aggregate-forming pili (AFP) mediates the aggregative adherence of a hybrid-pathogenic Escherichia coli (UPEC/EAEC) isolated from a urinary tract infection [PDF]

Virulence, 2021
Enteroaggregative Escherichia coli (EAEC) comprises an important diarrheagenic pathotype, while uropathogenic E. coli (UPEC) is the most important agent of urinary tract infection (UTI). Recently, EAEC virulence factors have been detected in E.
Rodrigo T Hernandes, Ulrich Dobrindt, Tania Gomes   +2 more
exaly   +3 more sources

Interleukin-6 Limits Host Susceptibility to Urinary Tract Infection by Promoting Urothelial Expulsion of Intracellular Bacteria [PDF]

Journal of Innate Immunity
Introduction: Interleukin (IL)-6 has an important role in limiting urinary tract infection (UTI). Mice lacking IL-6 are more susceptible to uropathogenic Escherichia coli (UPEC), including increased formation of intracellular bacterial ...
Sudipti Gupta, Shradha Rajak, Hanna Cortado, Brian Becknell, John David Spencer, Christina Barbara Ching   +5 more
doaj   +2 more sources

Bacteriophage-mediated reduction of uropathogenic E. coli from the urogenital epithelium [PDF]

Infection and Immunity
Urinary tract infections (UTIs), primarily caused by uropathogenic Escherichia coli (UPEC), affect millions annually. UPEC gains access to the urinary tract through mucosal reservoirs, including the vaginal tract.
Bishnu Joshi, Jacob J. Zulk, Camille Serchejian, Zainab A. Hameed, Addison B. Larson, Austen L. Terwilliger, Deepak Kumar, Indira U. Mysorekar, Robert A. Britton, Anthony W. Maresso, Kathryn A. Patras   +10 more
doaj   +2 more sources

Biomimickry of UPEC Cytoinvasion: A Novel Concept for Improved Drug Delivery in UTI [PDF]

Pathogens, 2016
Urinary tract infections (UTIs) are among the most common bacterial infections. In an increasing number of cases, pathogen (multi-)resistance hampers durable treatment success via the standard therapies. On the functional level, the activity of urinary excreted antibiotics is compromized by the efficient tissue colonization mechanism of uropathogenic ...
Lukas Neutsch, Bernhard Brauner, Michael Wirth   +2 more
exaly   +4 more sources

Cocktail of genetically diverse lytic phages reduces uropathogenic Escherichia coli colonization in mouse urinary tract [PDF]

Scientific Reports
Urinary tract infections (UTIs) caused by uropathogenic Escherichia coli (UPEC) are one of the most common bacterial infections in humans. The rise of multidrug-resistant UPEC strains increases the urgent need for alternative treatment. Two diverse lytic
Panupon Mongkolkarvin, Chutikarn Sukjoi, Watcharapol Suyapoh, Songphon Buddhasiri, Ifeoluwa Emmanuel Ilugbusi, Poochit Nonejuie, Michael Harrison Hsieh, Vorrapon Chaikeeratisak, Parameth Thiennimitr   +8 more
doaj   +2 more sources

Single-cell analysis reveals an important role of CD137L+ macrophages in the host response to uropathogenic Escherichia coli infection in the bladder. [PDF]

PLoS Pathogens
Uropathogenic Escherichia coli (UPEC) typically trigger rapid and robust innate immune responses in the bladder. In order to identify the key facets of the host response that influence pathogen clearance and tissue damage, single-cell RNA sequencing was ...
Yaxiao Liu, Zizhuo Yang, Yinrui Xiang, Guangzhou Cheng, Lipeng Chen, Shuai Wang, Maolin Zang, Nan Zhou, Xiaoyi Zhang, Rui Chen, Benkang Shi, Yan Li   +11 more
doaj   +2 more sources

Detection of fimH virulence gene in uropathogenic Escherichia coli Using PCR [PDF]

مجلة جامعة الانبار للعلوم الصرفة, 2020
Urinary tract infections (UTIs) are one of main health problems caused by many microorganisms, including uropathogenic Escherichia coli (UPEC). The virulence factors are important in colonization of UPEC, extra-intestinal survival, and creation of ...
Rawan Amer Fadhil
doaj   +1 more source

A Glimpse into the Resistant Pattern of Uropathogens: An Overview

Journal of Pure and Applied Microbiology, 2022
Urinary tract infection (UTI) poses a serious health issue for all age groups from neonates to geriatric age groups. Majority of the women experience urinary tract infections once in their lifetime.
Monalisa Debbarma, Birasen Behera, Bidyutprava Rout, Rajashree Panigrahy, Purabi Baral   +4 more
doaj   +1 more source

Molecular detection of genes encoding for adhesion factors in biofilm formation among uropathogenic Escherichia coli isolates

Medical Journal of Babylon, 2023
Background: The ability of Escherichia coli to build biofilms leads to the development of numerous diseases and makes their removal challenging. In addition to being the most common cause of urinary tract infections (UTIs), E.
Dina Hassan Abed Abbood, Zeena Hadi Obaid Alwan   +1 more
doaj   +1 more source

Phagocytosis and oxidative activity of neutrophils after interaction with uropathogenic Escherichia coli biofilms

Медицинская иммунология, 2023
Recurrent urinary tract infections (UTIs) are associated primarily with the ability of Escherichia coli to form biofilms. The interaction of neutrophils, factors of innate immunity, with microorganisms in biofilms is difficult compared to planktonic ...
I. L. Maslennikova, I. V. Nekrasova, M. V. Kuznetsova   +2 more
doaj   +1 more source