Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection [PDF]
, 2018 Significance The emergence of multidrug-resistant bacteria, including uropathogenic Escherichia coli (UPEC), makes the development of targeted antivirulence therapeutics a critical focus of research.
Chugani, Ryan +8 more
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Comparative proteomics of uropathogenic Escherichia coli during growth in human urine identify UCA-like (UCL) fimbriae as an adherence factor involved in biofilm formation and binding to uroepithelial cells [PDF]
, 2015 Uropathogenic Escherichia coli (UPEC) are the primary cause of urinary tract infection (UTI) in humans. For the successful colonisation of the human urinary tract, UPEC employ a diverse collection of secreted or surface-exposed virulence factors ...
Allsopp, LP +5 more
core +1 more source
When and where? Pathogenic Escherichia coli differentially sense host D-serine using a universal transporter system to monitor their environment [PDF]
, 2016 Sensing environmental stimuli is critically important for bacteria when faced with the multitude of adversities presented within the host. Responding appropriately to these signals and in turn integrating these responses into the regulatory network of ...
Connolly, James P.R., Roe, Andrew J.
core +2 more sources
A Population-Based Surveillance Study of Shared Genotypes of Escherichia coli Isolates from Retail Meat and Suspected Cases of Urinary Tract Infections. [PDF]
, 2018 There is increasing evidence that retail food may serve as a source of Escherichia coli that causes community-acquired urinary tract infections, but the impact of this source in a community is not known. We conducted a prospective, population-based study
Friedman, Cindy R +7 more
core +1 more source
The adherent/invasive escherichia coli (AIEC) strain LF82 invades and persists in human prostate cell lineRWPE-1 activating a strong inflammatory response [PDF]
, 2016 Adherent/invasive Escherichia coli (AIEC) strains have recently been receiving increased attention because they are more prevalent and persistent in the intestine of Crohn's disease (CD) patients than in healthy subjects.
ALEANDRI, MARTA +13 more
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Journal of Microbiology, Immunology and Infection, 2021 Background: Patients with diabetes mellitus (DM) have higher incidence and more severe urinary tract infections (UTIs) for longer duration than those of the patients without DM. It causes more complicated etiologies during uropathogenic Escherichia coli (
Chen-Hsun Ho +7 more
doaj +1 more source
BarA-UvrY two-component system regulates virulence of uropathogenic E. coli CFT073. [PDF]
PLoS ONE, 2012 Uropathogenic Escherichia coli (UPEC), a member of extraintestinal pathogenic E. coli, cause ∼80% of community-acquired urinary tract infections (UTI) in humans.
Senthilkumar Palaniyandi +6 more
doaj +1 more source
Cells, 2021 Understanding how uropathogenic Escherichia coli (UPEC) modulates the immune response in the kidney is essential to prevent UPEC from reaching the bloodstream and causing urosepsis.
Ashok Kumar Kumawat +3 more
doaj +1 more source
Escherichia coli-mediated impairment of ureteric contractility is uropathogenic E. coli specific. [PDF]
, 2012 BACKGROUND: Ureters are fundamental for keeping kidneys free from uropathogenic Escherichia coli (UPEC), but we have shown that 2 strains (J96 and 536) can subvert this role and reduce ureteric contractility. To determine whether this is (1) a widespread
Abe +34 more
core +2 more sources
Classification of multiple electromagnetic interference events in high-voltage power plant [PDF]
, 2018 This paper addresses condition assessment of electrical assets contained in high voltage power plants. Our work introduces a novel analysis approach of multiple event signals related to faults, and which are measured using Electro-Magnetic Interference ...
Boreham, Philip +5 more
core +2 more sources