Results 51 to 60 of about 31,787 (220)

Phylogenetic Distribution of Virulence Genes Among ESBL-producing Uropathogenic Escherichia coli Isolated from Long-term Hospitalized Patients [PDF]

Journal of Clinical and Diagnostic Research, 2015
Objectives: The present study was aimed to investigate the antibiotic resistance, virulence potential and phylogenetic grouping of ESBL-producing uropathogenic Escherichia coli (EP-UPEC) isolated from long-term hospitalized patients.
Ruike Zhao, Jinfang Shi, Yimin Shen, Yanmeng Li, Qingzhen Han, Xianfeng Zhang, Guohao Gu, Jie Xu   +7 more
doaj   +1 more source

UPEC Hemolysin: More than Just for Making Holes [PDF]

Cell Host & Microbe, 2012
During acute cystitis, uropathogenic Escherichia coli (UPEC) induce bladder epithelial cell exfoliation, which eliminates infected cells and promotes UPEC dissemination. Dhakal and Mulvey (2012) uncover the mechanism that induces this exfoliation and reintroduce the pore-forming toxin, hemolysin, as an effector that surprisingly targets multiple host ...
Justice, Sheryl S., Hunstad, David A.
openaire   +2 more sources

Virulence behavior of uropathogenic Escherichia coli strains in the host model Caenorhabditis elegans [PDF]

, 2018
Urinary tract infections (UTIs) are among the most common bacterial infections in humans. Although a number of bacteria can cause UTIs, most cases are due to infection by uropathogenic Escherichia coli (UPEC).
Amos, Anastasi, Anyanful, Barber, Barnich, Beutin, Blango, Brennan, Brenner, Brzuszkiewicz, Burton, Caldwell, Chen, Chávez, Chávez, Clermont, Croxen, Dale, Dho-Moulin, Diard, Doonan, Edgar, Ewers, Ferrières, Foxman, Francisco, Fricke, Guyer, Hagberg, Hoeven, Hornef, Johnson, Johnson, Johnson, Johnson, Kampkötter, Kaper, Kim, King, Kӧhler, Longhi, Mahajan-Miklos, Manges, Martinez-Medina, Merkx-Jacques, Mi, Mobley, Mulvey, Mylonakis, Müller, Paiva, Pidgeon, Powell, Sifri, Soto, Stepanović, Tan, Thumbikat, Valdivia, Wirth, Zanni   +60 more
core   +1 more source

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

Genetically diverse uropathogenic Escherichia coli adopt a common transcriptional program in patients with UTIs

eLife, 2019
Uropathogenic Escherichia coli (UPEC) is the major causative agent of uncomplicated urinary tract infections (UTIs). A common virulence genotype of UPEC strains responsible for UTIs is yet to be defined, due to the large variation of virulence factors ...
Anna Sintsova, Arwen E Frick-Cheng, Sara Smith, Ali Pirani, Sargurunathan Subashchandrabose, Evan S Snitkin, Harry Mobley   +6 more
doaj   +1 more source

Ybcl of uropathogenic escherichia coli suppresses transepithelial neutrophil migration [PDF]

, 2012
Uropathogenic Escherichia coli (UPEC) strains suppress the acute inflammatory response in the urinary tract to ensure access to the intracellular uroepithelial niche that supports the propagation of infection. Our understanding of this initial cross talk
Hunstad, David A, Lau, Megan E, Loughman, Jennifer A   +2 more
core   +2 more sources

One‐Year Effectiveness of Upadacitinib in Perianal Crohn's Disease: A Real‐World GETAID Study

Alimentary Pharmacology &Therapeutics, EarlyView.
In a real‐world cohort of patients with highly refractory perianal Crohn's disease, upadacitinib induced clinical remission at 12 months in 26% of patients with fistulizing disease and 25% of those with isolated anal ulcerations. ABSTRACT Introduction Upadacitinib (UPA) is effective for treating luminal Crohn's disease (CD), but data on perianal CD ...
Nicolas Richard, Philippe Seksik, Romain Altwegg, Maria Nachury, David Laharie, Stéphane Nancey, Benoît Coffin, Anne‐Laure Pelletier, Mathieu Uzzan, Aurélien Amiot, Morgane Amil, Lucine Vuitton, Mathurin Fumery, Anne Bozon   +13 more
wiley   +1 more source

The co-transcriptome of uropathogenic Escherichia coli-infected mouse macrophages reveals new insights into host-pathogen interactions [PDF]

, 2015
© 2014 The Authors. Cellular Microbiology published by John Wiley & Sons Ltd. Urinary tract infections (UTI) are among the most common infections in humans.
Beatson, SA, Bokil, NJ, Cannistraci, CV, Kakkanat, A, Mavromatis, C, Ravasi, T, Ryu, T, Schaale, K, Schembri, MA, Sweet, MJ, Totsika, M, Ulett, GC   +11 more
core   +3 more sources

Prognostic Factors in Patients With Submacular Haemorrhage Complicating Age‐Related Macular Degeneration: A Post Hoc Analysis of the STAR Study

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To investigate prognostic factors of recent submacular haemorrhage (SMH) complicating neovascular age‐related macular degeneration (nAMD) treated with surgery or pneumatic displacement combined with intravitreal injection of anti‐vascular endothelial growth factor.
Pierre‐Henry Gabrielle, Petra Eid, Ludwig Serge Aho, Laurent Kodjikian, Eric Souied, Joel Uzzan, Jean Baptiste Conart, Marie‐Noëlle Delyfer, Catherine Creuzot‐Garcher   +8 more
wiley   +1 more source

Phylogenetic diversity and virulence gene characteristics of Escherichia coli from pork and patients with urinary tract infections in Thailand.

PLoS ONE
Extraintestinal pathogenic Escherichia coli (ExPEC), especially uropathogenic E. coli (UPEC) are responsible for urinary tract infections (UTIs), while diarrheagenic E. coli (DEC) cause foodborne illnesses. These pathogenic E.
Pramualchai Ketkhao, Fuangfa Utrarachkij, Nattaya Parikumsil, Kritchai Poonchareon, Anusak Kerdsin, Peeraya Ekchariyawat, Pawarut Narongpun, Chie Nakajima, Yasuhiko Suzuki, Orasa Suthienkul   +9 more
doaj   +1 more source