Combinatorial small-molecule therapy prevents uropathogenic Escherichia coli catheter-associated urinary tract infections in mice [PDF]
, 2012 Catheter-associated urinary tract infections (CAUTIs) constitute the majority of nosocomial urinary tract infections (UTIs) and pose significant clinical challenges.
Caparon, Michael G +8 more
core +2 more sources
Water, water, every where—the advent of hydrated pili structure
The FEBS Journal, EarlyView.Protein structure is defined by its surrounding water. Naturally, this is also true for the gigantic protein filaments that pathogenic bacteria use to attach to and colonize their host cells. Structures of these filaments for which water can be identified with high confidence have stayed elusive for the longest time.
Hiroya Oki +3 more
wiley +1 more source
EBioMedicine, 2019 Background: Uropathogenic Escherichia coli (UPEC) is the leading cause of urinary tract infections (UTIs), and fimbrial tip adhesins, play important roles in UPEC colonization.
Xiao Li +10 more
doaj +1 more source
Bacterial lysis liberates the neutrophil migration suppressor YbcL from the periplasm of uropathogenic Escherichia coli [PDF]
, 2014 Uropathogenic Escherichia coli (UPEC) modulates aspects of the innate immune response during urinary tract infection to facilitate bacterial invasion of the bladder epithelium, a requirement for the propagation of infection.
Danka, Elizabeth S +3 more
core +2 more sources
French guidelines on systemic treatments for moderate‐to‐severe psoriasis in adults: Update 2025
Journal of the European Academy of Dermatology and Venereology, EarlyView.New 2025 French guidelines update psoriasis management with revised algorithms integrating recent systemic therapies. They recommend methotrexate, adalimumab or ustekinumab as first‐line treatments and provide guidance for special psoriasis forms, comorbidities, pregnancy and long‐term management.
Marie Masson Regnault +51 more
wiley +1 more source
Urinary ATP as an indicator of infection and inflammation of the urinary tract in patients with lower urinary tract symptoms [PDF]
, 2015 BACKGROUND: Adenosine-5'-triphosphate (ATP) is a neurotransmitter and inflammatory cytokine implicated in the pathophysiology of lower urinary tract disease. ATP additionally reflects microbial biomass thus has potential as a surrogate marker of urinary
A Kupelian +39 more
core +2 more sources
Plant, Cell &Environment, EarlyView.ABSTRACT The symbiosis between nitrogen‐fixing rhizobia and plants is considered mutually beneficial, yet its indirect effects on other organisms remain understudied. We examined how rhizobia symbiosis in Phaseolus vulgaris influences the behaviour and performance of Diabrotica balteata larvae. Specifically, we tested larval preference for nodulated (R+
Camilo Rivera +5 more
wiley +1 more source
Zanco Journal of Pure and Applied Sciences, 2020 Uropathogenic Escherichia coli (UPEC) is one of the most causative agents which causing urinary tract infections (UTIs) in humans. This study involved the prevalence of the virulence genes among UPEC isolated from patients in various hospitals in Zakho ...
Marwa Subhi Ibrahim +2 more
doaj +1 more source
H2: entanglement, probability density function, confined Kratzer oscillator, universal potential and (Mexican hat- or bell-type) potential energy curves [PDF]
, 2011 We review harmonic oscillator theory for closed, stable quantum systems. The H2 potential energy curve (PEC) of Mexican hat-type, calculated with a confined Kratzer oscillator, is better than the Rydberg-Klein-Rees (RKR) H2 PEC.
Van Hooydonk, G.
core +2 more sources
Transposon mutagenesis identifies uropathogenic Escherichia coli biofilm factors [PDF]
, 2012 Uropathogenic Escherichia coli (UPEC), which accounts for 85% of urinary tract infections (UTI), assembles biofilms in diverse environments, including the host.
Greene, Sarah E. +6 more
core +2 more sources