Results 51 to 60 of about 21,933 (182)

Phenotypic and genotypic characterization of Pseudomonas aeruginosa siderophores

Zagazig Journal of Pharmaceutical Sciences, 2018
Pseudomonas aeruginosa is an opportunistic human pathogen that causes many infections such as urinary tract, respiratory tract, burn infections in addition to septicemia.
Ashraf Kadry , Marwa Ezz , Hisham A. Abbas   +2 more
doaj   +1 more source

Natural combinatorial genetics and prolific polyamine production enable siderophore diversification in Serratia plymuthica

BMC Biology, 2021
Background Iron is essential for bacterial survival. Bacterial siderophores are small molecules with unmatched capacity to scavenge iron from proteins and the extracellular milieu, where it mostly occurs as insoluble Fe3+.
Sara Cleto, Kristina Haslinger, Kristala L. J. Prather, Timothy K. Lu   +3 more
doaj   +1 more source

Caractérisation des systèmes d'acquisition du fer de Staphylococcus aureus évaluation de cibles thérapeutiques pour le contrôle des mammites bovines [PDF]

, 2005
La mammite est une maladie responsable d'énormes pertes économiques pour l'industrie laitière. Malgré le fait que plusieurs espèces microbiennes peuvent l'induire, Staphylococcus aureus est de plus en plus le principal agent infectieux isolé des cas de ...
Blouin, Julie
core   +1 more source

Exploring the Roles of Tuna‐Associated Acinetobacter sp. YFT067: Implications for Host Health and Metabolism

Animal Research and One Health, EarlyView.
This study firstly isolated a tuna‐derived gut probiotic Acinetobacter seifertii YFT067. Dietary administration of YFT067 played significant roles in promoting growth performance, SCFAs production, lipid absorption, and metabolism of the host, indicating YFT067 as a promising probiotic candidate for enhancing tuna aquaculture productivity through ...
Ying Zou, Hai Huang, Qiongyao Fu, Zhiyuan Lu, Zhiqiang Guo   +4 more
wiley   +1 more source

Advances in Human Mass Balance Studies: An IQ Consortium Perspective on Current Practices and Emerging Trends

Clinical Pharmacology &Therapeutics, EarlyView.
Human radiolabeled mass balance studies are crucial for comprehensively characterizing the absorption, distribution, metabolism, and excretion (ADME) of investigational drugs, providing essential data for drug development, regulatory evaluation, and product labeling.
Jason Boer, Ellen Cannady, Filip Cuyckens, Ulrike Glaenzel, Camille Granvil, Felix Huth, Alexander D. James, Wenying Li, Céline Veau, Graeme Young, Qin Yue, Gregory S. Walker, Upendra A. Argikar, Jonathan N. Bauman, Cathy Cantalloube, Yu‐Luan Chen, Ping Kang, Patricia Moliner, Mette L. Pedersen, Isabel Piel, Simone Schadt, Hanno Schieferstein, Julia Suchomel, Shuai Wang, S. Cyrus Khojasteh   +24 more
wiley   +1 more source

Non-classical roles of bacterial siderophores in pathogenesis

Frontiers in Cellular and Infection Microbiology
Within host environments, iron availability is limited, which instigates competition for this essential trace element. In response, bacteria produce siderophores, secondary metabolites that scavenge iron and deliver it to bacterial cells via specific ...
Elliot Arnold
doaj   +1 more source

Possible Mechanisms of Action of Two Pseudomonas fluorescens Isolates as Probiotics on Saprolegniosis Control in Rainbow Trout (Oncorhynchus mykiss Walbaum)

Animals, 2020
Probiotics have been proposed as one of the alternatives to the chemical treatments currently used in aquaculture. Recently, the possible usefulness of certain microorganisms, mainly bacteria, has been highlighted as a potential biocontrol for ...
Concepción González-Palacios, Juan-Miguel Fregeneda-Grandes, José-Miguel Aller-Gancedo   +2 more
doaj   +1 more source

Microengineering the Liver: Strategies for Constructing Functional Liver‐on‐a‐Chip Devices

Exploration, EarlyView.
This review summarizes recent advances in liver‐on‐a‐chip (LOC) technologies, including fabrication strategies and functional integration approaches, and discusses their promising applications in drug screening and related biomedical fields. ABSTRACT Reliable in vitro liver models are indispensable for researching liver diseases and developing ...
Jie Wang, Ziwei Liang, Jiapu Wang, Zongyi Li, Shaojie Wang, Yan Wei, Xin Xie, Di Huang   +7 more
wiley   +1 more source

Advances in Mycobacterium siderophore-based drug discovery

Acta Pharmaceutica Sinica B, 2011
Tuberculosis remains a public health threat of global proportions. Iron is a scarce resource indispensable to both host and pathogen during infection with Mycobacterium tuberculosis, the causative agent of tuberculosis.
Jun-li He, Jian-ping Xie
doaj   +1 more source

Homéostasie des ions cuivre et fer au cours de la germination fongique. [PDF]

, 2019
La germination fongique est un processus cellulaire qui coordonne les changements métaboliques et morphologiques permettant à une spore en dormance de retrouver une forme végétative et une croissance mitotique. Les spores doivent jauger adéquatement leur
Plante, Samuel
core   +1 more source