Results 41 to 50 of about 33,615 (254)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Defeating Hardware Prefetchers in Flush+Reload Side-Channel Attack

IEEE Access, 2021
Hardware prefetching can seriously interfere with Flush+Reload cache side channel attack. This interference is not taken into consideration in previous Flush+Reload attacks.
Zihao Wang, Shuanghe Peng, Wenbin Jiang, Xinyue Guo   +3 more
doaj   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

EM Analysis in the IoT Context: Lessons Learned from an Attack on Thread

Transactions on Cryptographic Hardware and Embedded Systems, 2018
The distinguishing feature of the Internet of Things is that many devices get interconnected. The threat of side-channel attacks in this setting is less understood than the threat of traditional network and software exploitation attacks that are ...
Daniel Dinu, Ilya Kizhvatov
doaj   +1 more source

Behind the Scene of Side Channel Attacks [PDF]

, 2013
Since the introduction of side channel attacks in the nineties, a large amount of work has been devoted to their effectiveness and efficiency improvements. On the one side, general results and conclusions are drawn in theoretical frameworks, but the latter ones are often set in a too ideal context to capture the full complexity of an attack performed ...
Victor Lomné, Emmanuel Prouff, Thomas Roche   +2 more
openaire   +2 more sources

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Side-Channel Attacks on Cryptographic Software [PDF]

IEEE Security & Privacy Magazine, 2009
When it comes to cryptographic software, side channels are an often-overlooked threat. A side channel is any observable side effect of computation that an attacker could measure and possibly influence. Crypto is especially vulnerable to side-channel attacks because of its strict requirements for absolute secrecy.
openaire   +1 more source

Near Collision Side Channel Attacks [PDF]

, 2016
Side channel collision attacks are a powerful method to exploit side channel leakage. Otherwise than a few exceptions, collision attacks usually combine leakage from distinct points in time, making them inherently bivariate. This work introduces the notion of near collisions to exploit the fact that values depending on the same sub-key can have similar
Baris Ege, Thomas Eisenbarth 0001, Lejla Batina   +2 more
openaire   +2 more sources

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source