Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Prevalence of gastrointestinal side effects in hepatocellular carcinoma patients receiving sorafenib: a meta-analysis of 136 studies and 14,416 patients. [PDF]
Arendt N +5 more
europepmc +1 more source
Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source
Development of a Validated Lay Checklist (Info Without Side Effects) for Assessing Health Information on Websites: Mixed Methods Study. [PDF]
Griebler U +9 more
europepmc +1 more source
Nanozymes subvert pharmacological conventions: insights from counteracting the placental side effects of TiO₂ nanozymes. [PDF]
Zhang Y +10 more
europepmc +1 more source
Investigation of the administration technique and side effects of COVID-19 vaccines: a descriptive and cross-sectional study. [PDF]
Eyiler E, Terzi B, Koşar İ.
europepmc +1 more source
Prevalence and predictive testing preferences for breast cancer treatment side effects. [PDF]
McCall MK +4 more
europepmc +1 more source
Efficacy and side effects of long-term treatment strategies of canine primary hypoadrenocorticism. [PDF]
Dobosz DA, Zablotski Y, Wehner A.
europepmc +1 more source

