Results 51 to 60 of about 348,356 (277)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Defeating Hardware Prefetchers in Flush+Reload Side-Channel Attack

IEEE Access, 2021
Hardware prefetching can seriously interfere with Flush+Reload cache side channel attack. This interference is not taken into consideration in previous Flush+Reload attacks.
Zihao Wang, Shuanghe Peng, Wenbin Jiang, Xinyue Guo   +3 more
doaj   +1 more source

GazeTouchPIN: Protecting Sensitive Data on Mobile Devices Using Secure Multimodal Authentication [PDF]

, 2017
Although mobile devices provide access to a plethora of sensitive data, most users still only protect them with PINs or patterns, which are vulnerable to side-channel attacks (e.g., shoulder surfing). How-ever, prior research has shown that privacy-aware
Alt, Florian, Bulling, Andreas, Hassib, Mariam, Khamis, Mohamed, Zezschwitz, Emanuel von   +4 more
core   +1 more source

Frequency Throttling Side-Channel Attack

Proceedings of the 2022 ACM SIGSAC Conference on Computer and Communications Security, 2022
Modern processors dynamically control their operating frequency to optimize resource utilization, maximize energy savings, and conform to system-defined constraints. If, during the execution of a software workload, the running average of any electrical or thermal parameter exceeds its corresponding predefined threshold value, the power management ...
Liu, Chen, Chakraborty, Abhishek, Chawla, Nikhil, Roggel, Neer   +3 more
openaire   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

EM Analysis in the IoT Context: Lessons Learned from an Attack on Thread

Transactions on Cryptographic Hardware and Embedded Systems, 2018
The distinguishing feature of the Internet of Things is that many devices get interconnected. The threat of side-channel attacks in this setting is less understood than the threat of traditional network and software exploitation attacks that are ...
Daniel Dinu, Ilya Kizhvatov
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

DR.SGX: Hardening SGX Enclaves against Cache Attacks with Data Location Randomization

, 2019
Recent research has demonstrated that Intel's SGX is vulnerable to software-based side-channel attacks. In a common attack, the adversary monitors CPU caches to infer secret-dependent data accesses patterns. Known defenses have major limitations, as they
Brasser, Ferdinand, Capkun, Srdjan, Dmitrienko, Alexandra, Frassetto, Tommaso, Kostiainen, Kari, Sadeghi, Ahmad-Reza   +5 more
core   +1 more source