Results 111 to 120 of about 21,712,270 (345)
A study on the management of corticosteroid side effects in cancer patients [PDF]
, 2015 Background Systemic corticosteroids lead to many adverse effects especially in cancer patients. Preventive measures and treatment options are essential to minimise such side effects.
Fsadni, Clayton John
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Renal side effects of Ifosfamide in patients admitted for chemotherapy
Journal of Research in Medical Sciences, 2008 <ul> <li><strong>BACKGROUND</strong>: Ifosfamide (IFO) is an alkylating cytostatic agent with nephrotoxic properties. Most often it causes disturbances in proximal tubular function manifesting as glycosuria, albuminuria ...
Mohammad Ali Mashhadi
doaj
Prolactin Elevation Due to Sertraline Use in a Patient with Pituitary Adenoma: A Case Report
Ahi Evran Medical JournalAntipsychotics are the drugs that most frequently cause prolactinemia among the psychiatric drug groups. When prolactin eleva tion is mentioned, it is generally considered as a side effect related to antipsychotics.
Meltem Puşuroğlu +2 more
doaj +1 more source
Minoxidil induced hypertrichosis in children
The Pan African Medical Journal, 2014 Minoxidil is a strong arterial vasodilator used in the treatment of hypertension. In dermatology, topic minoxidil is widely used to treat hair fall. Hypertrichosis may occur if this form is misused.
Najwa Guerouaz, Ait Ourhroui Mohamed
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
World Journal of Nuclear Medicine, 2016 Iodine-131 (I-131) therapy is one of the conventional approaches in the treatment of patients with differentiated thyroid carcinoma (DTC). The radioiodine agents also accumulate in the other organs that cause pain and damage to the patients.
Mehran Pashnehsaz +6 more
doaj +1 more source
CHECKPOINT INHIBITOR IMMUNE THERAPY: Systemic Indications and Ophthalmic Side Effects
Retina, 2018 Purpose: To review immune checkpoint inhibitor indications and ophthalmic side effects. Methods: A literature review was performed using a PubMed search for publications between 1990 and 2017.
L. Dalvin +4 more
semanticscholar +1 more source