Comment on: Immune checkpoint inhibitor therapy for treatment of periocular Merkel cell carcinoma - Exploring ocular side effects. [PDF]
Sanjay S.
europepmc +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
Gastrointestinal Side Effects of Low-Dose Oral Minoxidil in Patients with Alopecia: An Underrecognized Association. [PDF]
Soares J +2 more
europepmc +1 more source
Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn +2 more
wiley +1 more source
Web questionnaire survey of physicians and patients on the side effects of trifluridine/tipiracil. [PDF]
Nakajima TE +4 more
europepmc +1 more source
Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto +14 more
wiley +1 more source
Inflammatory Markers Associated with Antidepressant-Related Side Effects in Patients with Major Depressive Disorder: A Cross-Sectional Study. [PDF]
Çankaya İnan E, Bulut M, Uyar B.
europepmc +1 more source

