Results 211 to 220 of about 2,166,400 (310)

Correction to: Acute side effects of proton and photon radiotherapy for medulloblastoma: a retrospective national multicenter study. [PDF]

J Neurooncol
Diaz LS, Agrup M, Asklid A, Embring A, Engellau J, Kristensen IF, Flejmer A, Fröjd C, Nilsson MP, Svärd AM, Walfridsson A, Blomstrand M.   +11 more
europepmc   +1 more source

A novel LQT5 transgenic rabbit model for the assessment of proarrhythmic side effects of developmental compounds. [PDF]

, 2014
István Baczkó, Viktor Juhász, Peter Major, Mária Kovács, Tibor Hornyik, András Varró, László Hiripi, Bősze, Z.   +7 more
openalex  

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Oral side effects of dermatologic therapies: A systematic review and meta-analysis. [PDF]

Bioinformation
M Alqahtani R, Ahmad Farhan MA, M Almutiari S, Fajr Ehab AA, Abdulmohsen Abdulkarim FA, Zwiri A, Sghaireen MG, Alam MK.   +7 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Reliability and validity of the Chinese Version of the Frequency, Intensity, and Burden of Side Effects Rating. [PDF]

Front Psychiatry
Zhao J, Ji J, Cao A, Ni J, Cao T.
europepmc   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Premaxillary Fat Pads on Magnetic Resonance Imaging (MRI) as a Marker of Steroid Side Effects. [PDF]

Cureus
A R, Goel T, Garg P, Peer S, Wander A.
europepmc   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source