Results 41 to 50 of about 4,809,367 (307)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
工程科学与技术, 2013 :Geddes’s solution is one of a comment approach to estimate the settlement of subsoil of pile foundation.In order to obtain more precious results,a modified Geddes’s solution was performed as the assumptions that the end resistance uniformly distribute ...
吕亚茹 +4 more
doaj
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Consumer Resistance in the Pet Marketplace [PDF]
This study draws on Cherrier’s (2008) concept of consumer-resistant identities together with the work of Beverland, Farelly and Lim (2008) on the dark side of pet ownership to shed light on consumer resistance in the context of the pet marketplace.
McEachern, Morven G., Cheetham, Fiona
core +3 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Field study on the application of combined grouting for the super-long drilled shaft
Results in Engineering, 2023 According to the field static loading test performed on the super-long drilled shaft, the influence of combined grouting on bearing capacity and displacement control ability of super-long drilled shaft was explored.
Tong Wang +4 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Evaluation of trimaran side hull angles on forward resistance
Annals of "Dunărea de Jos" University of Galaţi: Fascicle XI Shipbuilding, 2016 This project reflects the authors’ view on the influence of the side hulls rotation with respect to X and Z axis on trimaran’s total forward resistance.
Liviu Galatanu +2 more
doaj
Assessment of field rolling resistance of manual wheelchairs [PDF]
, 2012 This article proposes a simple and convenient method for assessing the subject-specific rolling resistance acting on a manual wheelchair, which could be used during the provision of clinical service.
BASCOU, Joseph +5 more
core +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source