Results 91 to 100 of about 288,483 (243)
Diagnosis and Classification of Myelodysplastic Syndrome [PDF]
, 2019 Myelodysplastic syndrome (MDS) is a clonal hematopoietic stem cell disorder characterized by morphological dysplastic changes in one or more of the major hematopoietic cell lines.
Al-Nehmi, Abdul Wahab +2 more
core +1 more source
Ibrain, Volume 10, Issue 4, Page 395-426, Winter 2024.This review elucidates the pivotal role of RNA modifications in the etiology and progression of neurodegenerative disorders. RNA modification proteins (RMPs) including FTO, HNRNPA2B1, ADAR1/2, METTL3/14, NSUN2, and ALKBH5 are implicated in initiating dysregulated RNA modifications, thereby disrupting RNA metabolism.
Muhammad Abu Talha Safdar Hashmi +4 more
wiley +1 more source
Characterizing Aft1/2-Grx3/4 Interaction and the Role of Bol2 During Iron Regulation in Saccharomyces cerevisiae [PDF]
, 2019 Iron dysregulation has been linked to a variety of human diseases, such as anemia, Friedreich’s ataxia, X-linked sideroblastic anemia, sideroblastic-like microcytic anemia, and myopathy.
Rivers, William
core +1 more source
Association between biomarkers of zinc and copper status and heart failure: a meta‐analysis
ESC Heart Failure, Volume 11, Issue 5, Page 2546-2556, October 2024.Abstract Aims Previous studies have investigated the relationship between heart failure (HF) and levels of zinc and copper, but conflicting results have been reported. This meta‐analysis aims to clarify the role of zinc and copper in HF progression by examining the associations between HF and concentrations of these minerals.
Ruixin Liu +3 more
wiley +1 more source
Hereditary Ataxia: A Focus on Heme Metabolism and Fe-S Cluster Biogenesis [PDF]
, 2020 Heme and Fe-S clusters regulate a plethora of essential biological processes ranging from cellular respiration and cell metabolism to the maintenance of genome integrity.
Bertino, Francesca +2 more
core +1 more source
Prediction the Occurrence of Thalassemia With Hematological Phenotype by Diagnosis of Abnormal HbA1c
Journal of Clinical Laboratory Analysis, Volume 38, Issue 19-20, October 2024.Patients participated in hemoglobin A1c (HbA1c) testing in clinical laboratory showing high hemoglobin F (HbF) levels (≥ 1.5%) or abnormal Hb peak got mutations and showed younger age, lower Hb, MCV and MCH levels, higher RBC count, and PDW than patients without thalassemia mutations.
Yafang Wan +4 more
wiley +1 more source
Медицинский совет, 2016 Iron overload (RV) is a condition caused by excessive intake of iron, and in the absence of the specific mechanisms for its excretion - excessive accumulation in tissues and their subsequent lesion leading to functional organ failure [1].
M. V. Krasolnikova
doaj +1 more source
Acquired Myelodysplasia or Myelodysplastic Syndrome: Clearing the Fog [PDF]
, 2013 Myelodysplastic syndromes (MDS) are clonal myeloid disorders characterized by progressive peripheral blood cytopenias associated with ineffective myelopoiesis.
David Pyatt, Ethan A. Natelson
core +2 more sources
American Journal of Hematology, Volume 99, Issue 8, Page 1511-1522, August 2024.Abstract Congenital Dyserythropoietic Anemia type I (CDA I) is a rare hereditary condition characterized by macrocytic/normocytic anemia, splenomegaly, iron overload, and distinct abnormalities during late erythropoiesis, particularly internuclear bridges between erythroblasts.
Roberta Marra +14 more
wiley +1 more source
Antibody-mediated acquired sideroblastic anemia: response to cytotoxic therapy [PDF]
, 1979 A. Kim Ritchey +5 more
openalex +3 more sources