ALAS2 Prevents Neonatal Necrotizing Enterocolitis by Improving Ferroptosis in Intestinal Epithelial Cells Through Inhibition of Oxidative Stress [PDF]
Mediators of InflammationNeonatal necrotizing enterocolitis (NEC) is an intestinal disease that occurs in the neonatal period. The purpose of this study was to investigate the role of 5′-aminolevulinate synthase 2 (ALAS2) in NEC-induced intestinal injury.
Zenghui Hao +8 more
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5‐Aminolevulinic‐Acid Synthetase of Rhodopseudomonas spheroides Y [PDF]
European Journal of Biochemistry, 1973 The two species of 5‐aminolevulinic acid synthetase were purified about 4200‐fold for fraction I and about 2000‐fold for fraction II. They were obtained homogenous in disc electrophoresis. These two enzymes have the same molecular weight (about 100 000) and contain one molar equivalent of pyridoxal phosphate.
M, Fanica-Gaignier, J, Clement-Metral
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5-Aminolevulinic-Acid Synthetases from Rhodopseudomonas spheroides Y. Comparison of the Purification and Properties of Enzymes Extracted from Bacteria Grown in Different Iron Concentrations [PDF]
European Journal of Biochemistry, 1975 The two 5-aminolevulinic acid synthetases of Rhodopseudomonas spheroides Y. were extracted from cells grown in a 'low-iron' medium and purified. They have a specific activity 10-fold higher than the 'high-iron' enzymes described by us previously and have the same properties except that they do not contain any iron and have one free-SH group more per ...
J D, Clement-Metral, F, Fanica-Gaignier
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Anais Brasileiros de Dermatologia, 2010 A terapia fotodinâmica é uma reação química ativada por luz usada para destruição seletiva de um tecido e requer um agente fotossensibilizante no tecido-alvo, uma fonte de luz e oxigênio.
Maria Cláudia Almeida Issa +1 more
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Complex formation between glutamyl‐tRNA synthetase and glutamyl‐ tRNA reductase during the tRNA‐dependent synthesis of 5‐aminolevulinic acid in Chlamydomonas reinhardtii [PDF]
FEBS Letters, 1992 The formation of a stable complex between glutamyl‐tRNA synthetase and the first enzyme of chlorophyll biosynthesis glutamyl‐tRNA reductase was investigated in the green alga Chlamydomonas reinhardtii. Apparently homogenous enzymes, purified after previously established purification protocols were incubated in various combinations with ATP, glutamate ...
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Frontiers in MicrobiologyIntroduction 5-Aminolevulinic acid (5-ALA) is a nonprotein amino acid with broad applications in agriculture, medicine, and the food industry. In recent years, substantial efforts have been devoted to enhancing its biosynthesis.
Yang, Peng +7 more
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Elucidation of the Late Steps during Hexacosalactone A Biosynthesis in Streptomyces samsunensis OUCT16-12. [PDF]
Appl Environ Microbiol, 2023 Duan H +6 more
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Impact of Efavirenz on Heme Protein Induction and Biomarkers: Insights From In Vitro Experiments and a Clinical Study. [PDF]
Clin Transl SciPotzel L +5 more
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Systems metabolic engineering of dual pathways with stage-specific activation for high-level 5-aminolevulinic acid production in <i>Escherichia coli</i>. [PDF]
Synth Syst BiotechnolLiu Y +9 more
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Metabolic Engineering of the 5-Aminolevulinate Biosynthetic Pathway in E. coli Improves Efficiency of Hemoprotein-Based Biocatalysis. [PDF]
Angew Chem Int Ed EnglKato S +6 more
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