Results 31 to 40 of about 84,609,228 (161)
-pyrroline-5-carboxylate synthetase in two safflower cultivars
, 2010 Proline (Pro) accumulation under water stress was measured in safflower (Carthamus tinctorius L.) drought tolerant cv. A1 and sensitive cv. Nira. Activities of pyrroline-5-carboxylate reductase (P5C reductase) and pyrroline-5-carboxylate synthetase (P5C ...
M. Thippeswamy +4 more
core +1 more source
Heme-dependent Inactivation of 5-Aminolevulinate Synthase from Caulobacter crescentus
Scientific Reports, 2018 The biosynthesis of heme is strictly regulated, probably because of the toxic effects of excess heme and its biosynthetic precursors. In many organisms, heme biosynthesis starts with the production of 5-aminolevulinic acid (ALA) from glycine and succinyl-
H. Ikushiro +8 more
semanticscholar +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: Transporters
British Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +28 more
wiley +1 more source
Journal of Inherited Metabolic Disease, Volume 48, Issue 5, September 2025.ABSTRACT Cobalamin (vitamin B12) is an essential cofactor for two human enzymes, methionine synthase and methylmalonyl‐CoA mutase. Inborn errors of cobalamin metabolism (IECMs) are inherited genetic defects resulting in improper transport, modification, or utilization of cobalamin and include inherited methylmalonic acidurias, a group of IECMs most ...
Almut Heinken +5 more
wiley +1 more source
Biochemistry, 2015 Regulation of 5-aminolevulinate synthase (ALAS) is at the origin of balanced heme production in mammals. Mutations in the C-terminal region of human erythroid-specific ALAS (hALAS2) are associated with X-linked protoporphyria (XLPP), a disease ...
Erica J. Fratz +9 more
semanticscholar +1 more source
Environmental Microbiology, Volume 27, Issue 9, September 2025.An intense green algal proliferation with severe ecological consequences occurred during the winter season in one of the largest lagoons on the French Mediterranean coast. The study contributes to the understanding of the rise and resilience of the tiny photosynthetic eukaryote, which thrived in cool waters under low solar radiance.
Béatrice Bec +9 more
wiley +1 more source
Frontiers in Microbiology, 2015 A combined approach, comprising PCR screening and genome mining, was used to unravel the diversity and phylogeny of genes encoding 5-aminolevulinic acid synthases (ALASs, hemA gene products) in streptomycetes-related strains.
K. Petříčková +6 more
semanticscholar +1 more source
Drug Testing and Analysis, Volume 17, Issue 8, Page 1417-1442, August 2025.Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario Thevis +2 more
wiley +1 more source
Continuous coupled assay for 5-aminolevulinate synthase
, 1997 This chapter discusses the continuous coupled assay for 5-aminolevulinate synthase. A direct 5-aminolevulinate synthase enzyme assay has been developed on the basis of linking 5-aminolevulinate synthase to pyruvate dehydrogenase.
LeLean, Jeremy E. +5 more
core +1 more source