Results 51 to 60 of about 84,609,228 (161)
Apicoplast‐Resident Processes: Exploiting the Chink in the Armour of Plasmodium falciparum Parasites
Advances in Pharmacological and Pharmaceutical Sciences, Volume 2024, Issue 1, 2024.The discovery of a relict plastid, also known as an apicoplast (apicomplexan plastid), that houses housekeeping processes and metabolic pathways critical to Plasmodium parasites’ survival has prompted increased research on identifying potent inhibitors that can impinge on apicoplast‐localised processes.
Collins Ojonugwa Mamudu +6 more
wiley +1 more source
Photodynamic therapy with methyl aminolevulinate in the treatment of basal cell carcinoma
, 2017 The article presents the results of the studies on the effectiveness of treatment basal cell carcinoma of the skin with photodynamic therapy with 5-aminolevulinic acid and methyl aminolevulinate.
N. V. Gribanov +2 more
core +1 more source
Methods For The Identification Of Inhibitors Of 5-Aminolevulinate Synthase As Antibiotics [PDF]
, 2004 The Present Inventors Have Discovered That 5-Aminolevulinate Synthase Is Essential For Fungal Pathogenicity. Specifically, The Inhibition Of 5-Aminolevulinate Synthase Gene Expression In Fungi Results In No Signs Of Successful Infection Or Lesions. Thus,
core
, 1987 Administration of Prudhoe Bay crude oil (PBCO) to rats resulted in a dose-related (i) increase in liver weight; (ii) rapid and marked increase in the activity of hepatic δ-aminolevulinate synthetase, the initial and rate-limiting enzyme in the heme ...
A. D. Rahimtula, S. Khan
core +1 more source
METHODS FOR THE IDENTIFICATION OF INHIBITORS OF 5-AMINOLEVULINATE SYNTHASE AS ANTIBIOTICS [PDF]
, 2003 The present inventors have discovered that 5-Aminolevulinate synthase is essential for fungal pathogenicity. Specifically, the inhibition of 5-Aminolevulinate synthase gene expression in fungi results in no signs of successful infection or lesions. Thus,
core
International Journal of Dermatology, 2013 A 70-year-old male patient with generalized tumor-stage mycosis fungoides (MF) presented to our office. He had been treated with psoralen + ultraviolet A, bexarotene, and total-skin electron beam radiation with poor response.
Ariel Hasson +3 more
semanticscholar +1 more source
Molecular enzymology of 5-Aminolevulinate synthase, the gatekeeper of heme biosynthesis
Biochimica et Biophysica Acta, 2011 Pyridoxal-5'-phosphate (PLP) is an obligatory cofactor for the homodimeric mitochondrial enzyme 5-aminolevulinate synthase (ALAS), which controls metabolic flux into the porphyrin biosynthetic pathway in animals, fungi, and the α-subclass of ...
Gregory A. Hunter, G. C. Ferreira
semanticscholar +1 more source
Localization of γ-Glutamylcysteine Synthetase and Glutathione Synthetase Activity in Maize Seedlings [PDF]
, 1993 Fresh weight, protein, cysteine, γ-glutamylcysteine, glutathione, and the extractable activity of the enzymes of glutathione biosynthesis, γ-glutamylcysteine synthetase (EC 6.3.2.2) and glutathione synthetase (EC 6.3.2.3), were measured in roots ...
Brunold, Christian +3 more
core +2 more sources
Radiochemical assay for δ-aminolevulinate synthase
, 1982 We describe here a standard protocol for the radiochemical assay of δ-aminolevulinate synthase from 17-day chick embryo liver mitochondria and starved male rat liver mitochondria.
May, BK +7 more
core +1 more source
Hydrogenation of Geranylgeraniol. Two Pathways Exist in Spinach Chloroplasts [PDF]
, 1983 The reduction of geranylgeranylpyrophosphate to phytylpyrophosphate in spinach chloroplasts is described for the first time. The reductase is localized in the chloroplast envelope.
Soll, Jürgen +3 more
core +1 more source