Results 141 to 150 of about 3,469 (181)

Meme biosynthesis in sideroblastic anemia

International Journal of Biochemistry, 1980
Abstract The activities of δ-aminolevulinic acid synthase (ALA-S), δ-aminolevulinic acid dehydratase (ALA-D), uroporphyrinogen I synthase (Uro-I-S), uroporphyrinogen decarboxylase (Uro-DC) and heme synthase have been studied in peripheral red blood cells of 9 patients with hereditary sideroblastic anemia (HSA) and 8 patients with refractory ...
A V, Pasanen, M, Salmi, P, Vuopio, R, Tenhunen   +3 more
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Cytogenetic studies in sideroblastic anemia

Cancer, 1976
Cytogenetic studies were performed on bone marrow aspirates from seven patients with acquired sideroblastic anemia. In one male patient a 45,X cell line was present in each of three bone marrow aspirates. The remaining six patients had a normal chromosome complement. The abnormal stem line in the bone marrow may be unrelated to the hematologic disorder
M K, Jensen, M, Mikkelsen
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The molecular basis of the sideroblastic anemias

Current Opinion in Hematology, 1996
The sideroblastic anemias display remarkable clinical and hematologic heterogeneity but share in common mitochondrial iron loading as evidence of unhinging between intracellular iron metabolism and heme biosynthesis. Molecular defects responsible for this unhinging have now been identified and appear to display matching heterogeneity.
E J, Fitzsimons, A, May
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Zinc abuse and sideroblastic anemia

American Journal of Hematology, 1993
AbstractWe report the case of a young woman who presented with anemia and leukopenia. A bone marrow aspirate, revealed a marked excess of ringed sideroblasts. A detailed dietary history disclosed excessive zinc intake. High serum zinc and low serum copper concentrations were confirmed.
J, Ramadurai, C, Shapiro, M, Kozloff, M, Telfer   +3 more
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Sideroblastic anemia and development of leukemia

Blut, 1981
In patients with refractory anemia it is important to count and classify the different sideroblasts (intermediate sideroblasts with more than six iron grains or ring sideroblasts), to study the cellularity of the bone marrow and disturbances in thrombo- and myelopoiesis, and to note previous exposure to mutagenic or other toxic agents.
R, Hast, P, Reizenstein
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Sideroblastic anemias

Hematology Meeting Reports, 2009
The sideroblastic anemias are a heterogeneous group of inherited and acquired disorders characterized by anemia of varying severity and the presence of ringed sideroblasts in the bone marrow.1 These latter are immature red cells with iron-loaded mitochondria visualized by Prussian blue staining as a perinuclear ring of blue granules. The most common of
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Sideroblastic Anemia

JAMA: The Journal of the American Medical Association, 1987
P I, Liu, J Y, Lim
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Hereditary Sideroblastic Anemia

Hospital Practice, 1991
V F, Fairbanks, E R, Dickson, M E, Thompson   +2 more
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[Sideroblastic anemias].

Orvosi hetilap, 1992
The sideroblastic anaemias form a group of disorders of varying aetiology. They are being recognized with increasing frequency, especially as routine staining of bone marrow films for iron is now standard practice in most foreign laboratories. The sideroblastic anaemias have as a common feature the presence of large numbers of pathologic (ringed ...
I, Bernát Sándor, M, Hartai, E, Kormányos, I, Bernát   +3 more
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[Sideroblastic anemia].

Ryoikibetsu shokogun shirizu, 1999
A, Gotoh, K, Ohyashiki
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