Results 101 to 110 of about 110,940 (229)

Optimisation of a Novel Class of DNA Gyrase Inhibitors to Improve Antibacterial Activity

ChemMedChem, Volume 21, Issue 11, 15 June 2026.
This article describes efforts to increase the antibacterial activity of a recently reported class of novel DNA gyrase inhibitors known as the isoquinoline sulphonamides by improving their uptake in bacterial cells. As antibiotic resistance continues to rise, the need for new antibacterials is clear.
Meg I. Ferguson, Cerissa C. van Walstijn, Vladyslav Lysenko, Marta A. Wilbrink, David Alencar Araripe, Jeroen M. Punt, Mario van der Stelt, Willem Jespers, Paolo Innocenti, Nathaniel I. Martin   +9 more
wiley   +1 more source

Iron and Virulence in Stenotrophomonas Maltophilia: All We Know So Far

Frontiers in Cellular and Infection Microbiology, 2018
Stenotrophomonas maltophilia is a multi-drug-resistant global opportunistic nosocomial pathogen, which possesses a huge number of virulence factors and antibiotics resistance characteristics. Iron has a crucial contribution toward growth and development,
V. Kalidasan, Narcisse Joseph, Suresh Kumar, Rukman Awang Hamat, Vasantha Kumari Neela   +4 more
doaj   +1 more source

Contribution of siderophore systems to growth and urinary tract colonization of asymptomatic bacteriuria Escherichia coli [PDF]

, 2012
The molecular mechanisms that define asymptomatic bacteriuria (ABU) E. coli colonization of the human urinary tract remain to be properly elucidated. Here we utilize ABU E.
Totsika, Makrina, Ulett, Glen C., Makrina Totsika, Glen C. Ulett, Ulett, Glen C, Schembri, Mark A, Mabbett, Amanda N., Rebecca E. Watts, Mark A. Schembri, Challinor, Victoria L, Watts, Rebecca E, Ulett, Glen, Mabbett, Amanda N, James J. De Voss, Challinor, Victoria L., De Voss, James J., Schembri, Mark A., Amanda N. Mabbett, Watts, Rebecca E., Mabbett, Amada N., De Voss, James J, Victoria L. Challinor   +21 more
core   +1 more source

Inhibition of the Flavin-Dependent Monooxygenase Siderophore A (SidA) Blocks Siderophore Biosynthesis and Aspergillus fumigatus Growth

, 2016
Aspergillus fumigatus is an opportunistic fungal pathogen and the most common causative agent of fatal invasive mycoses. The flavin-dependent monooxygenase siderophore A (SidA) catalyzes the oxygen and NADPH dependent hydroxylation of l-ornithine (l-Orn)
Kim Harich, Pablo Sobrado, Harich, Kim, Karina Kizjakina, Julia S. Martín del Campo, Sobrado, Pablo, Tolani, Karishma, Vogelaar, Nancy, Kizjakina, Karina, Karishma Tolani, Martín Del Campo, Julia S., Nancy Vogelaar   +11 more
core   +1 more source

Petrobactin Protects against Oxidative Stress and Enhances Sporulation Efficiency in Bacillus anthracis Sterne

mBio, 2018
Bacillus anthracis is a Gram-positive bacillus that under conditions of environmental stress, such as low nutrients, can convert from a vegetative bacillus to a highly durable spore that enables long-term survival. The sporulation process is regulated by
Ada K. Hagan, Yael M. Plotnick, Ryan E. Dingle, Zachary I. Mendel, Stephen R. Cendrowski, David H. Sherman, Ashootosh Tripathi, Philip C. Hanna   +7 more
doaj   +1 more source

Characterisation of siderophore producing marine bacteria

, 2013
Marine bacteria are diverse and highly abundant in the oceans. Under iron-depleted conditions, marine bacteria produce an iron chelator called a siderophore to scavenge for iron.
Dahse, Anne-Kristin
core   +1 more source

Siderophore mediated absorption of iron

, 2010
A brief presentation of iron chemistry is made with emphasis on those aspects relevant to siderophore biochemistry. Siderophore structure and biosynthesis is described.
Rider, Robert C.
core  

Bacterial siderophore production on lignin-derived aromatic compounds

, 2023
Lignin is a highly branched, recalcitrant polymer found in plant cell walls and is a major waste product of the pulp and paper industry. There is interest in lignin valorization through microbial transformation using bacteria capable of growing on lignin-
Newman, Brianne
core  

Siderophore production by uropathogenic Escherichia coli

Indian Journal of Pathology and Microbiology, 2009
Urinary tract infection (UTI) is one of the most frequently encountered problems in ambulatory medicine. The present study was designed to determine siderophore production as the urovirulence factor of Escherichia coli isolated from the patients of UTI ...
Vagrali Manjula
doaj  

Specificity and mechanism of TonB-dependent ferric catecholate uptake by Fiu

Frontiers in Microbiology
We studied the Escherichia coli outer membrane protein Fiu, a presumed transporter of monomeric ferric catecholates, by introducing Cys residues in its surface loops and modifying them with fluorescein maleimide (FM).
Taihao Yang, Ye Zou, Ho Leung Ng, Ashish Kumar, Salete M. Newton, Phillip E. Klebba   +5 more
doaj   +1 more source