Results 131 to 140 of about 131,773 (290)

Pseudotetraivprolides from Pseudomonas entomophila Provide Insights into the Biosynthesis of Detoxin/Rimosamide‐Like Anti‐Antibiotics

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 4, 22 January 2026.
Pseudotetraivprolide is a new player among the Detoxin/Rimosamide‐like natural products! Its biosynthesis requires FabD from primary metabolism and a PipDFG complex for final‐step acetylation – unlocking its anti‐antibotic activity. Abstract Novel variants of known natural product (NP) classes can provide valuable insights into their biosynthesis ...
Edna Bode   +13 more
wiley   +1 more source

OxyR-regulated T6SS functions in coordination with siderophore to resist oxidative stress

open access: yesMicrobiology Spectrum
The formation of reactive oxygen species is harmful and can destroy intracellular macromolecules such as lipids, proteins, and DNA, even leading to bacterial death. To cope with this situation, microbes have evolved a variety of sophisticated mechanisms,
Changfu Li   +9 more
doaj   +1 more source

Exploitation of siderophores for the speciation of iron [PDF]

open access: yes, 2011
Iron is essential for life. It acts as an electron donor/acceptor in metabolic processes facilitated by its variable valency. Although vital, it is toxic at high levels due to Fe2+ oxidation. Iron toxicity is a concern as it can affect growth and product
Clarke, Paul A.   +5 more
core  

A New Approach to Characterize Siderophore-Type Ligands in Seawater by Solid Phase Synthesis and SPE-HPLC-ESI-MS/MS Analysis

open access: yesJournal of Marine Science and Engineering
Siderophores are organic ligands involved in dissolved iron (dFe) speciation in the oceans. Their study is crucial for a better understanding of the biogeochemical cycle of Fe in the marine environment, particularly in certain areas, such as the Southern
Paola Rivaro   +5 more
doaj   +1 more source

In Silico Analysis of the Ga3+/Fe3+ Competition for Binding the Iron-Scavenging Siderophores of P. aeruginosa—Implementation of Three Gallium-Based Complexes in the “Trojan Horse” Antibacterial Strategy

open access: yesBiomolecules
The emergence of multidrug-resistant (MDR) microorganisms combined with the ever-draining antibiotic pipeline poses a disturbing and immensely growing public health challenge that requires a multidisciplinary approach and the application of novel ...
Nikoleta Kircheva   +5 more
doaj   +1 more source

Siderophores as tools and treatments

open access: yesnpj Antimicrobials and Resistance
AbstractIn the search for iron, an essential element in many biochemical processes, microorganisms biosynthesise dedicated chelators, known as siderophores, to sequester iron from their environment and actively transport the siderophore complex into the cell.
Á. Tamás Gräff, Sarah M. Barry
openaire   +3 more sources

Siderophore production by uropathogenic Escherichia coli

open access: yesIndian Journal of Pathology and Microbiology, 2009
Urinary tract infection (UTI) is one of the most frequently encountered problems in ambulatory medicine. The present study was designed to determine siderophore production as the urovirulence factor of Escherichia coli isolated from the patients of UTI ...
Vagrali Manjula
doaj  

Speciation and Mobilization of Toxic Heavy Metal Ions by Methanogenic Bacteria [PDF]

open access: yes, 1993
HWRIC Project HWR 92 ...
Conver, Shawn   +5 more
core  

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