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Chemistry and biology of siderophores

Natural Product Reports, 2010
Siderophores are compounds produced by bacteria, fungi and graminaceous plants for scavenging iron from the environment. They are low-molecular-weight compounds (500-1500 daltons) possessing a high affinity for iron(III) (Kf > 1030), the biosynthesis of which is regulated by iron levels and the function of which is to supply iron to the cell.
Hider, Robert C., Kong, Xiaole
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Siderophores and Transferrins

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
E.A. Dertz, K.N. Raymond
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Intracellular siderophore but not extracellular siderophore is required for full virulence in Metarhizium robertsii

Fungal Genetics and Biology, 2015
Efficient iron acquisition mechanisms are fundamental for microbial survival in the environment and for pathogen virulence within their hosts. M. robertsii produces two known iron-binding natural products: metachelins, which are used to scavenge extracellular iron, and ferricrocin, which is strictly intracellular.
Bruno, Giuliano Garisto Donzelli   +2 more
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Bacterial siderophores promote plant growth: Screening of catechol and hydroxamate siderophores

International Journal of Phytoremediation, 2017
The aim of the study was to determine the quality and quantity of siderophores produced by bacteria isolated from plants' roots. The second aim was to determine the effect of siderophores on plants growth (Festuca rubra L. and Brassica napus L.). The study was carried out using bacteria isolated from roots of: Arabidopsis thaliana L., F.
Anna, Grobelak, Joanna, Hiller
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Microbial siderophores: a mini review

Journal of Basic Microbiology, 2012
AbstractIron is one of the major limiting factors and essential nutrients of microbial life. Since in nature it is not readily available in the preferred form, microorganisms produce small high affinity chelating molecules called siderophores for its acquisition. Microorganisms produce a wide variety of siderophores controlled at the molecular level by
Ratul, Saha   +3 more
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Siderophore-dependent ferrichelatases

Iron is a crucial secondary metabolite for bacterial proliferation, but its bioavailability under infection conditions is limited by the low solubility of ferric ion and the host's ability to sequester iron by protein chelation. In these iron limiting conditions, bacteria produce and secrete low molecular weight ferric ion chelators, siderophores, to ...
C E, Merrick   +2 more
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Siderophores in Fungal Physiology and Virulence

Annual Review of Phytopathology, 2008
Maintaining the appropriate balance of iron between deficiency and toxicity requires fine-tuned control of systems for iron uptake and storage. Both among fungal species and within a single species, different systems for acquisition, storage, and regulation of iron are present.
Hubertus, Haas   +2 more
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Methodology of siderophores

2007
Siderophores, defined as iron(III) specific transport compounds, are widely distributed in aerobic and facultative anaerobic microbial species. The list of microbes known to form siderophores includes various enteric bacteria; human, animal and plant pathogenic bacteria and fungi; soil microorganisms; Gram positive and negative species, blue green alga
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Ecology of Siderophores

2014
This chapter attempts to illustrate the occurrence of siderophores within different bacterial genera and explains the relationship between environmental factors and the biological function of siderophores, which may be summarized under the term "ecology of siderophores".
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Siderophore production by Salmonella typhi

Biochemical and Biophysical Research Communications, 1988
This study was initiated to determine the mechanism of iron-uptake in Salmonella typhi. When stressed for iron, microorganisms produce siderophores to obtain the necessary nutrient. Generally two types of siderophores exist: the phenolate-type predominantly produced by bacteria and the hydroxamate-type commonly secreted by fungi.
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