Results 41 to 50 of about 110,940 (229)

Molecular mechanism of siderophore regulation by the Pseudomonas aeruginosa BfmRS two-component system in response to osmotic stress

Communications Biology
Pseudomonas aeruginosa, a common nosocomial pathogen, relies on siderophores to acquire iron, crucial for its survival in various environments and during host infections.
Yingjie Song, Xiyu Wu, Ze Li, Qin qin Ma, Rui Bao   +4 more
doaj   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

T2T Genome Assembly and Multi‐Omics Data Reveal Terrestrial Adaptation and Mucus Biosynthesis in Tropical Leatherleaf Slug (Laevicaulis alte)

Advanced Science, EarlyView.
A gap‐free genome assembly and multi‐omics comparison of the terrestrial slug Laevichaulis alte with an aquatic relative reveal that expansion of the VEGF family orchestrates mucus production, lipid metabolism, and immune defense—highlighting key molecular innovations for conquering life on land.
Gang Wang, Shaofang He, Zhongkai Wang, Aobo Pang, Xiaoli Sun, Rongchen Liu, Fang Wang, Sisi Chen, Zhijuan Bian, Dongcheng Wei, Liuhan Wu, Siyao Zhao, Qiuting Ji, Yiqi Sun, Niying Sun, Yushinta Fujaya, Boping Tang, Kianann Tan, Daizhen Zhang, Lianfu Chen   +19 more
wiley   +1 more source

Distribution of siderophore biosynthetic systems relative to siderophore production.

, 2015
Significance tests were performed comparing the top and bottom quartiles using the Fischer’s exact test.
Guillaume Méric (543892), Ida Porcelli (700407), Sacha Lucchini (6756), Laura J. Searle (700406), Samuel K. Sheppard (124129)   +4 more
core   +1 more source

Exploring the Roles of Tuna‐Associated Acinetobacter sp. YFT067: Implications for Host Health and Metabolism

Animal Research and One Health, EarlyView.
This study firstly isolated a tuna‐derived gut probiotic Acinetobacter seifertii YFT067. Dietary administration of YFT067 played significant roles in promoting growth performance, SCFAs production, lipid absorption, and metabolism of the host, indicating YFT067 as a promising probiotic candidate for enhancing tuna aquaculture productivity through ...
Ying Zou, Hai Huang, Qiongyao Fu, Zhiyuan Lu, Zhiqiang Guo   +4 more
wiley   +1 more source

Identification and characterisation of novel iron acquisition mechanisms in Sinorhizobium meliloti 2011 and Pseudomonas aeruginosa [PDF]

, 2003
All known microorganisms with the exception of lactobacilli display an absolute requirement for iron. Although iron is the fourth most abundant element on earth, it is rapidly oxidised at neutral pH forming insoluble hydroxides.
Ó Cuív, Páraic
core  

Evolution of rhizobial siderophore utilization via accessory xeno-siderophore receptors and flexible intake machinery for self-produced siderophores. [PDF]

ISME J
Abstract Bradyrhizobium and Sinorhizobium are dominant soybean microsymbionts in acidic/neutral and alkaline soils, respectively. However, the molecular mechanisms underlying this pH-dependent adaptation remain elusive. In this study, phylogenomic analysis of 286 Bradyrhizobium and 322 Sinorhizobium genomes revealed that ...
Si YW, Feng MD, Yang BS, Liu YN, Liu KH, Wang Y, Jiao J, Tian CF.   +7 more
europepmc   +4 more sources

Homo‐/Heterodimeric Substrates Bias the Type and Multiplicity of Hydroxamic Acid Chelators Assembled by a NIS Synthetase DesD

Chemistry – A European Journal, EarlyView.
Chemoenzymatic reactions using the siderophore synthetase DesD from Salinispora tropica and hydroxamic acid substrates (native, non‐native) with different multiplicities (monomer, dimer) and components (homo‐/heterodimer) followed different reaction trajectories, which biased the architectures of the chelator major products and indicated DesD contains ...
Callum A. Rosser, Todd E. Markham, Rachel Codd   +2 more
wiley   +1 more source

Metabolomic analysis of siderophore cheater mutants reveals metabolic costs of expression in uropathogenic escherichia coli

, 2014
Bacterial siderophores are a group of chemically diverse, virulence-associated secondary metabolites whose expression exerts metabolic costs. A combined bacterial genetic and metabolomic approach revealed differential metabolomic impacts associated with ...
Hung, Chia S., Henderson, Jeffrey P., Lv, Haitao   +2 more
core   +1 more source

Unraveling the mechanisms behind the enhanced efficacy of β-lactam-based sideromycins

Communications Biology
Previous studies have explored combining β-lactams with siderophores to create Trojan horse molecules that can penetrate the outer membrane of Gram-negative bacteria via TonB-dependent transporter (TBDT).
Evelyne Lacasse, Renaud Binette, Héloïse Guibout, Riu Liu, Yun-Ming Lin, Manuka Ghosh, Pierre-Luc Boudreault, Marvin J. Miller, François Malouin   +8 more
doaj   +1 more source