Results 161 to 170 of about 10,055 (203)

Synthese und aktivitätsbasierte Proteinprofilierung identifizieren die Aldo‐Keto‐Reduktase 1C3 als Zielprotein der Myxoglucamide

Angewandte Chemie, Volume 138, Issue 41, 5 October 2026.
Myxoglucamid A – ein neuartiges, aus Myxobakterien isoliertes Glykolipopeptid – wurde erstmals totalsynthetisch hergestellt. Mittels aktivitätsbasierter Proteinprofilierung (ABPP) wurde die Aldo‐Keto‐Reduktase 1C3 (AKR1C3) als primäres Zielprotein in menschlichen Zellen identifiziert.
Thomas Siemon, Vivek K. Mishra, Mingming Zhao, Konrad Büssow, Alexander Popoff, Chengzhang Fu, Rolf Müller, Lothar Jänsch, Wulf Blankenfeldt, Mark Brönstrup   +9 more
wiley   +1 more source

Trait-based analysis of yield formation and nitrogen use efficiency in wheat genotypes under integrated organic and NPK fertilization in low-fertility sandy soil. [PDF]

BMC Plant Biol
Zaire MAIA, El-Banna AYA, Omar AEEA, El-Sobky EEA, Attia MA, El-Tarabily KA, AbuQamar SF, Mansour E.   +7 more
europepmc   +1 more source

Synthesis and Activity‐Based Protein Profiling Identifies Aldo‐Keto Reductase 1C3 as Target Protein of Myxoglucamides

Angewandte Chemie International Edition, Volume 65, Issue 41, 5 October 2026.
Myxoglucamide A—a novel glycolipopeptide isolated from myxobacteria—was synthesized, and activity‐based protein profiling identified aldo‐keto reductase 1C3 (AKR1C3) as its main target in human cells. Structure‐activity relationship studies, together with biophysical characterization and X‐ray crystallography, elucidated the structural basis of AKR1C3 ...
Thomas Siemon, Vivek K. Mishra, Mingming Zhao, Konrad Büssow, Alexander Popoff, Chengzhang Fu, Rolf Müller, Lothar Jänsch, Wulf Blankenfeldt, Mark Brönstrup   +9 more
wiley   +1 more source

A compact Marx generator based on shock ionization dynistors. [PDF]

iScience
Korotkov S, Aristov Y, Zhmodikov A, Korotkov D.   +3 more
europepmc   +1 more source

Small islands as system and scale to examine the One Health concept. [PDF]

Bioscience
Koenig XGH, Florens FBV, Iranah P, Tatayah V, Deenapanray PNK.   +4 more
europepmc   +1 more source

A Case of Sudden Unexpected Infant Death with Presumptive SARS-CoV-2 Infection. [PDF]

Int J Mol Sci
Galichina VA, Nasyrov RA, Davydova ZV, Gabaraev SE, Yagmurov OD.   +4 more
europepmc   +1 more source

Infant Mortality in Norway: A Population-Based Study From 2009 Through 2020. [PDF]

Acta Paediatr
Eriksen BH, Klingenberg C, Myklebust TÅ.   +2 more
europepmc   +1 more source

Mammalian Diving Response in Humans: Inconsistently Beneficial for Survival. [PDF]

Cureus
Hayman J, Dodd M.
europepmc   +1 more source

Perinatal Depression and Infant Mortality.

JAMA Netw Open
Woofter R, McGovern ME, Abe N, Rokicki S.   +3 more
europepmc   +1 more source

Review of How the Advice to Reduce Sudden Infant Death Syndrome Was Developed, Including Its Dramatic Impact on Sweden. [PDF]

Acta Paediatr
Wennergren G.
europepmc   +1 more source