Results 41 to 50 of about 42,685 (291)

Evaluation of an Electronic Case-based Disease Surveillance System in Karene District, Sierra Leone

open access: yesJournal of Interventional Epidemiology and Public Health
Introduction: In 2018, the Government of Sierra Leone introduced an electronic Case-based Disease Surveillance System (eCBDS) to enhance timely data collection, analysis, and dissemination for outbreak detection.
Eldred Olufemi Moore   +8 more
doaj   +1 more source

Diagnostic challenges and implications of a Yellow Fever co-infected with Malaria case in Freetown, Sierra Leone, September 2023: An outbreak investigation

open access: yesJournal of Interventional Epidemiology and Public Health
Introduction: Yellow fever is one of the epidemic-prone and immediately reportable diseases in Sierra Leone. On September 7, 2023, the Western Area Urban District Surveillance Unit received a notification on a suspected yellow fever case from Connaught ...
Umaru Sesay   +5 more
doaj   +1 more source

Dose‐dependent pathogenicity and inflammatory imbalance in severely immunodeficient mice infected with mpox virus

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study establishes an NPG (NOD.Cg‐Prkdcscid Il2rgtm1/Vst) mouse model for severe monkeypox virus infection in immunocompromised hosts, demonstrating dose‐dependent disease severity and revealing that unbalanced pro‐inflammatory cytokine release drives pathogenesis, providing insights for therapeutic interventions. Abstract The global spread of mpox
Na Li   +11 more
wiley   +1 more source

Leveraging target enrichment and genome skimming (Hyb‐Seq) of herbarium collections to unlock timber DNA barcoding

open access: yesApplications in Plant Sciences, EarlyView.
Abstract Premise DNA barcoding for timber species identification requires comprehensive reference datasets, informative DNA barcodes, and cost‐effective protocols. We developed a workflow leveraging Hyb‐Seq (target capture sequencing and genome skimming) to address these challenges, and we tested it on four genera from the mahogany family (Meliaceae ...
Sidonie Bellot   +14 more
wiley   +1 more source

Developmental differences in cortical bone structure in chimpanzee and human femora reflect early locomotor independence in humans

open access: yesThe Anatomical Record, EarlyView.
Abstract The cortical bone structure of long bone diaphyses changes throughout growth via skeletal modeling and has important implications for bone strength and structural integrity. Ontogenetic trends in diaphyseal structure have been identified in both chimpanzees and humans but it is not yet clear how these trends compare given notable differences ...
Karen R. Swan   +3 more
wiley   +1 more source

The effect of the COVID-19 pandemic on routine immunization services in Sierra Leone, 2021

open access: yesJournal of Interventional Epidemiology and Public Health
Introduction: The COVID-19 pandemic resulted in movement and service restrictions during 2020 and 2021 that may have affected the essential immunization services in Sierra Leone.
Kassim Kamara   +5 more
doaj   +1 more source

Evaluating the (comparative) safety profile of the novel oral polio vaccine type 2 using individual case safety reports in VigiBase

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar   +6 more
wiley   +1 more source

Impact of Covid-19 on journalism in Sierra Leone. National survey report 2021 [PDF]

open access: yes, 2021
This rapid response report presents findings from a national survey undertaken to ascertain the impact of Covid-19 on Sierra Leone journalists. Sierra Leone was among the nations that took swift action, declaring a 12-month state of national emergency in
Baker-Beall, Christopher   +5 more
core  

Digital Transformation and Informal Innovation in Africa: Reframing STI Policy for Inclusive Circular Economy Transitions

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Amid increasing environmental and economic pressures, Africa's transition to a circular economy (CE) presents a vital pathway to inclusive, low‐carbon development. Yet, how digital transformation, informal innovation, and science, technology, and innovation (STI) policy readiness shape CE outcomes remains underexplored.
Emmanuel K. Manu   +2 more
wiley   +1 more source

Factors associated with antiretroviral therapy default in the 34-Military Hospital, Sierra Leone, 2017-2020

open access: yesJournal of Interventional Epidemiology and Public Health
Introduction: Antiretroviral therapy (ART) is a group of medicines used to treat people living with Human Immunodeficiency Virus (HIV). ART reduces the mortality and morbidity of people living with HIV. Defaulting on ART means an HIV-positive patient who
Henry Bangura   +4 more
doaj   +1 more source

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