Results 41 to 50 of about 71,736 (261)

Dry sieving analysis of soil by vibratory sieve shaker: modification and optimization

Dokuchaev Soil Bulletin, 2019
This study performs a methodical experiment on adaptation and unification of soil dry sieving analysis. The analysis is based on the Savvinov dry sieving method that uses 0.5-1.5 kg air-dried soil samples which are passed through the 10, 7, 5, 3, 2, 1, 0.5, 0.25 mm sieves. The studied soils are silt loam Eutric Retisol and Haplic Chernozem.
D. S. Fomin, I. A. Valdes-Korovkin, A. P. Holub, A. V. Yudina   +3 more
openaire   +3 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Rigorous analysis of a randomised number field sieve [PDF]

Journal of Number Theory, 2018
Factorisation of integers $n$ is of number theoretic and cryptographic significance. The Number Field Sieve (NFS) introduced circa 1990, is still the state of the art algorithm, but no rigorous proof that it halts or generates relationships is known. We propose and analyse an explicitly randomised variant.
Lee, Jonathan D., Venkatesan, Ramarathnam   +1 more
openaire   +3 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Investigation of the fungal community structures of imported wheat using high-throughput sequencing technology.

PLoS ONE, 2017
This study introduced the application of high-throughput sequencing techniques to the investigation of microbial diversity in the field of plant quarantine.
Yaqian Shi, Yinghui Cheng, Ying Wang, Guiming Zhang, Ruifang Gao, Caiyu Xiang, Jianjun Feng, Dingfeng Lou, Ying Liu   +8 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Digital Image-Based Rapid Determination and Analysis of Grain Size Distribution of Concrete Aggregates and Rock Fills

Buildings
Digital image-based determination of aggregate and rock gradation has been only limitedly addressed in the existing literature despite its considerable potential to transform conventional material characterization practices in civil engineering.
Muhammet Karabulut, Tugba Palabas, Dragan Marinkovic   +2 more
doaj   +1 more source

On the Sieve Analysis of Tea

Chagyo Kenkyu Hokoku (Tea Research Journal), 1958
In order to determine the grain-size of tea, the sieve analysis of tea was examined with J. I. S. standard sieves. The test sieves used had openings of 500-5, 660μ in √2 magnifi-cation series. On measuring the grain-size distribution of tea, 50g. of tea were sieved for 5min. with Ro-Tap shaker, and the residue on each sieve was weighed.
Toshio HARA, Etsuro KUBOTA, Saneyuki KAYUMI   +2 more
openaire   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source