Results 61 to 70 of about 257,723 (287)

On Primes Represented by Quadratic Polynomials

, 2007
This is a survey article on the Hardy-Littlewood conjecture about primes in quadratic progressions. We recount the history and quote some results approximating this hitherto unresolved conjecture.Comment: six(6) pages, minor changes were ...
Baier, Stephan, Zhao, Liangyi
core   +5 more sources

Passive phloem loading and long-distance transport in a synthetic tree-on-a-chip [PDF]

, 2017
Vascular plants rely on differences of osmotic pressure to export sugars from regions of synthesis (mature leaves) to sugar sinks (roots, fruits). In this process, known as M\"unch pressure flow, the loading of sugars from photosynthetic cells to the ...
A Lang, A Schulz, AC Srivastava, AD Stroock, BR Bruhn, BT Good, C Zhang, E Münch, J Liesche, JP Wright, JP Wright, JR Lancashire, KH Jensen, KH Jensen, KH Jensen, KH Jensen, KH Jensen, KH Jensen, M Knoblauch, M Knoblauch, MV Thompson, N Gould, P Dechadilok, PJ Kramer, Q Fu, R Turgeon, R Turgeon, R Turgeon, RT Giaquinta, S Herrlich, T Velten, TD Wheeler, W Eschrich, WA Russin, X Noblin, Y Gamalei, Z-R Xu   +36 more
core   +2 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

On the Sieve Analysis of Tea

Chagyo Kenkyu Hokoku (Tea Research Journal), 1958
In order to determine the grain-size of tea, the sieve analysis of tea was examined with J. I. S. standard sieves. The test sieves used had openings of 500-5, 660μ in √2 magnifi-cation series. On measuring the grain-size distribution of tea, 50g. of tea were sieved for 5min. with Ro-Tap shaker, and the residue on each sieve was weighed.
Toshio HARA, Etsuro KUBOTA, Saneyuki KAYUMI   +2 more
openaire   +2 more sources

Polignac Numbers, Conjectures of Erd\"os on Gaps between Primes, Arithmetic Progressions in Primes, and the Bounded Gap Conjecture [PDF]

, 2013
In the present work we prove a number of surprising results about gaps between consecutive primes and arithmetic progressions in the sequence of generalized twin primes which could not have been proven without the recent fantastic achievement of Yitang ...
Pintz, Janos
core  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Electrophysiological approach to determine kinetic parameters of sucrose uptake by single sieve elements or phloem parenchyma cells in intact Vicia faba plants

Frontiers in Plant Science, 2013
Apart from a few using cut aphid stylets, no attempts have been made thus far to measure in vivo sucrose-uptake properties of sieve elements. We investigated the kinetics of sucrose uptake by single sieve elements and phloem parenchyma cells in Vicia ...
Jens B. Hafke, Sabina-Roxana eHöll, Christina eKühn, Aart J.E. Van Bel   +3 more
doaj   +1 more source

Levels of Distribution and the Affine Sieve

, 2014
This article is an expanded version of the author's lecture in the Basic Notions Seminar at Harvard, September 2013. Our goal is a brief and introductory exposition of aspects of two topics in sieve theory which have received attention recently: (1) the ...
Kontorovich, Alex
core   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source