Results 61 to 70 of about 71,736 (261)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Vortex Cleaning Device for Rice Harvester: Design and Bench Test
AgricultureTo solve the problem of increased grain impurity rate and grain loss rate caused by clogging of sieve holes during the cleaning process of ratooning rice, a spiral step cleaning device was designed, which disturbed the flow field at the sieve holes ...
Weijian Liu, Shan Zeng, Xuegeng Chen
doaj +1 more source
Comparison of the effectiveness of selected medical segregation systems - START, SIEVE, CAREFLIGHT
Critical Care Innovations, 2019 INTRODUCTION: In the face of sudden events with many victims, various types of medical segregation systems were created. Their aim is to set the treatment and transport priority of patients by giving them appropriate urgency codes considering their ...
Monika Klepacka +3 more
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
P-proteins in Arabidopsis are heteromeric structures involved in rapid sieve tube sealing
Frontiers in Plant Science, 2013 Structural phloem proteins (P-proteins) are characteristic components of the sieve elements in all dicotyledonous and many monocotyledonous angiosperms.
Stephan B Jekat +6 more
doaj +1 more source
Causal inference methods for vaccine sieve analysis with effect modification. [PDF]
Stat Med, 2022 Yang G, Balzer LB, Benkeser D.
europepmc +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Sieve analysis to understand how SARS-CoV-2 diversity can impact vaccine protection. [PDF]
PLoS Pathog, 2021 Rolland M, Gilbert PB.
europepmc +1 more source